Diflucan 50 Mg Capsules

Diflucan 50 Mg Capsules

Description:

Diflucan 50 mg capsules are an oral prescription antifungal medicine containing fluconazole, manufactured by Pfizer. Fluconazole is a triazole antifungal agent used to treat and prevent a wide range of fungal and yeast infections in adults and children, including Candida and Cryptococcus infections. Diflucan works by inhibiting fungal cell membrane synthesis, helping to clear infection and relieve associated symptoms such as soreness, white patches, itching, and discomfort. It is commonly used in hospital and outpatient settings as part of systemic antifungal therapy under medical supervision.

Indications:

• Treatment of oropharyngeal candidiasis (oral thrush) – white patches, soreness, burning sensation in the mouth or throat caused by Candida species.
• Treatment of oesophageal candidiasis – Candida infection of the esophagus causing painful swallowing, chest discomfort, and difficulty swallowing.
• Treatment and prevention of recurrent vaginal candidiasis (vaginal thrush) – itching, burning, abnormal discharge caused by Candida.
• Treatment of systemic candidiasis, including candidemia and disseminated Candida infections affecting internal organs.
• Treatment of cryptococcal infections, including cryptococcal meningitis (infection of the membranes around the brain and spinal cord) in immunocompromised patients.
• Prophylaxis of fungal infections in patients with weakened immune systems (e.g., chemotherapy, radiotherapy, bone marrow transplant, advanced HIV infection), as prescribed by a physician.
• Other fungal infections caused by susceptible organisms, as determined by the treating physician.

Active Ingredients / Key Components:

• Fluconazole – 50 mg per capsule.
• Excipients (inactive ingredients): The full list of capsule excipients (e.g., fillers, capsule shell components, colorants) is not specified in the provided information. Please refer to the official package leaflet for a complete ingredient list.

Dosage & Administration / How to Use:

• Diflucan 50 mg capsules are for oral use only and should be taken exactly as prescribed by your doctor.
• Swallow the capsule whole with a glass of water. Do not crush or chew the capsule.
• Can be taken with or without food. If stomach upset occurs, taking it with food may help.
• Typical adult dosing (to be individualized by a physician):
  • Oropharyngeal candidiasis: Often an initial higher dose on day 1 followed by 50 mg once daily for at least 7–14 days, or as directed by the doctor.
  • Oesophageal candidiasis: Dose and duration are usually higher and longer than for oral thrush; your doctor will determine the exact regimen.
  • Vaginal candidiasis: Dose and duration may vary; sometimes used as part of a multi-dose or maintenance regimen.
  • Systemic candidiasis and cryptococcal infections: Higher doses than 50 mg are usually required; 50 mg strength may be used as part of a titrated regimen or maintenance therapy under specialist supervision.
  • Prophylaxis in immunocompromised patients: Dose and duration depend on the level of immunosuppression and risk of fungal infection.
• Pediatric use: Dosing in children is based on body weight (mg/kg) and must be strictly determined by a pediatrician. Do not use in children without medical advice.
• Take the medicine at the same time each day to maintain consistent blood levels.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Complete the full course of treatment even if symptoms improve early, to prevent recurrence and resistance.

Clinical Benefits:

• Provides broad-spectrum antifungal activity against many Candida and Cryptococcus species, helping to clear fungal and yeast infections effectively.
• Helps relieve symptoms of fungal infections such as itching, burning, soreness, white patches, and discomfort in the mouth, throat, or genital area.
• Suitable for systemic treatment of serious fungal infections, including bloodstream and deep-organ candidiasis, when prescribed by a specialist.
• Useful for prevention of fungal infections in high-risk immunocompromised patients (e.g., chemotherapy, transplant, advanced HIV), reducing the risk of opportunistic infections.
• Oral capsule form allows convenient once-daily dosing in many indications, supporting better adherence to therapy.

Warnings & Contraindications:

• Do not use Diflucan 50 mg capsules if you are allergic (hypersensitive) to fluconazole, other azole antifungals (such as ketoconazole, itraconazole), or any of the excipients in the product.
• Contraindicated with certain medicines that can cause serious heart rhythm problems when combined with fluconazole (e.g., some QT-prolonging drugs). Always inform your doctor about all medications you are taking.
• Use with caution in patients with liver disease or a history of liver problems. Fluconazole can cause liver toxicity; liver function tests may be required during prolonged therapy.
• Use with caution in patients with kidney impairment; dose adjustment may be necessary because fluconazole is primarily excreted by the kidneys.
• May cause QT prolongation and rare serious cardiac arrhythmias, especially in patients with existing heart disease, electrolyte disturbances (low potassium, magnesium), or when combined with other QT-prolonging drugs.
• Important drug interactions:
  • Cimetidine: May decrease efficacy of fluconazole.
  • Cyclosporine: May increase cyclosporine plasma concentration; monitoring and dose adjustment may be required.
  • Hydrochlorothiazide: May reduce renal clearance of fluconazole, increasing its levels.
  • Phenytoin: Fluconazole may enhance phenytoin levels; monitoring is advised.
  • Rifampicin: May decrease fluconazole efficacy; higher fluconazole doses may be required under medical supervision.
  • Sulfonylureas (e.g., tolbutamide, glyburide, glipizide): Risk of enhanced hypoglycemic effect; blood glucose monitoring is recommended.
  • Warfarin: Potentiates anticoagulant effect and increases prothrombin time; INR monitoring and dose adjustment may be necessary.
• Consult your doctor before use if you are pregnant, planning pregnancy, or breastfeeding. Fluconazole use in pregnancy requires careful risk–benefit assessment.
• Inform your doctor if you have HIV/AIDS, cancer, are on chemotherapy, have had an organ transplant, or any condition that weakens your immune system.
• Do not self-medicate for serious or recurrent fungal infections; always use under medical supervision.
• Keep out of reach of children.
• This product is a prescription medicine and should be used only under the guidance of a qualified healthcare professional.
• Not intended to diagnose, treat, cure, or prevent any disease without appropriate medical supervision.

Side Effects:

• Common side effects: Headache, nausea, stomach pain, diarrhea, indigestion, flatulence, changes in taste, mild skin rash.
• Less common but important side effects: Elevated liver enzymes, hepatitis, jaundice (yellowing of skin or eyes), severe skin reactions, dizziness.
• Serious side effects – seek immediate medical attention: Signs of liver problems (persistent nausea, vomiting, abdominal pain, dark urine, pale stools, yellowing of skin/eyes), severe skin reactions (widespread rash, blistering, peeling), difficulty breathing, swelling of face, lips, tongue, or throat (allergic reaction), irregular heartbeat, fainting.
• If you experience any unusual or persistent side effects, contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Store at or below the temperature specified on the package insert (specific temperature range is not provided here; refer to the official leaflet).

Specifications:

• Strength: 50 mg fluconazole per capsule.
• Form: Hard gelatin capsule for oral administration.
• Pack size: 7 capsules per pack (DIFLUCAN 50 MG 7 CAPS.).
• Product type: Prescription antifungal medicine.
• Manufacturer: Pfizer.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.