Downoprazol 20 Mg 14 Capsules

Downoprazol 20 Mg 14 Capsules

Description:

Downoprazol 20 mg 14 capsules is a prescription-only gastric acid–suppressing medicine containing omeprazole and sodium bicarbonate. It belongs to the class of proton pump inhibitors (PPIs) and is used to reduce excess stomach acid, relieve heartburn, and promote healing of acid-related disorders such as gastric and duodenal ulcers and gastroesophageal reflux disease (GERD). The added sodium bicarbonate provides rapid buffering of stomach acid and protects omeprazole from degradation in the acidic environment, allowing effective absorption and faster symptom relief. It is intended for adult use under medical supervision.

Indications:

• Treatment of duodenal ulcer and gastric ulcer.
• Management of gastroesophageal reflux disease (GERD) and reflux-related heartburn and regurgitation.
• Treatment of erosive oesophagitis and reflux oesophagitis.
• Relief of acid-related dyspepsia (acid indigestion, epigastric pain, burning sensation in the upper abdomen) as directed by a physician.
• Management of Zollinger–Ellison syndrome and other pathological hypersecretory conditions, as prescribed.
• Prevention and treatment of non-steroidal anti-inflammatory drug (NSAID)–associated gastric and duodenal ulceration.
• Prophylaxis of acid aspiration during anesthesia in selected patients, according to medical advice.

Active Ingredients / Key Components:

• Omeprazole – 20 mg per capsule (proton pump inhibitor that suppresses gastric acid secretion).
• Sodium bicarbonate – 1100 mg per capsule (systemic antacid and buffer that neutralizes gastric acid and protects omeprazole from acid degradation).
• Other inactive ingredients/excipients: Not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.). Full excipient list is not available.

Dosage & Administration / How to Use:

• Use exactly as prescribed by your physician. Do not exceed the recommended dose or duration.
• Typical adult dose for GERD, heartburn, or peptic ulcer disease: 1 capsule (20 mg omeprazole/1100 mg sodium bicarbonate) once daily, usually in the morning. Your doctor may adjust the dose or frequency based on your condition.
• For severe or resistant conditions (e.g., Zollinger–Ellison syndrome), higher or more frequent dosing may be required strictly under specialist supervision.
• Take the capsule on an empty stomach, at least 30–60 minutes before a meal (usually before breakfast), unless your doctor advises otherwise.
• Swallow the capsule whole with a full glass of water. Do not crush or chew the capsule.
• If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed one.
• Duration of treatment varies: short-term (2–4 weeks) for uncomplicated heartburn or ulcers, and longer courses for chronic GERD or hypersecretory conditions, as directed by your doctor.
• Not recommended for children unless specifically prescribed by a pediatric specialist.

Clinical Benefits:

• Provides potent and sustained reduction of gastric acid secretion by irreversible inhibition of the gastric proton pump (H+ / K+ ATPase) in parietal cells.
• Relieves symptoms of heartburn, acid reflux, sour regurgitation, and epigastric pain associated with GERD and acid dyspepsia.
• Promotes healing of gastric and duodenal ulcers and helps prevent recurrence when used as directed.
• Helps protect the stomach and duodenum from damage associated with long-term NSAID use.
• Assists in controlling excessive acid production in conditions such as Zollinger–Ellison syndrome.
• Combination with sodium bicarbonate offers faster onset of symptom relief by neutralizing existing stomach acid while omeprazole takes effect.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to omeprazole, other proton pump inhibitors, sodium bicarbonate, or any component of the formulation.
• Use with caution in patients with severe liver impairment; dose adjustment and close medical supervision may be required.
• Use with caution in patients with heart failure, kidney disease, edema, or conditions requiring sodium restriction, as sodium bicarbonate adds extra sodium load.
• Long-term use of proton pump inhibitors may be associated with increased risk of bone fractures (hip, wrist, spine), vitamin B12 deficiency, hypomagnesemia, and gastrointestinal infections (e.g., Clostridioides difficile). Periodic medical review is recommended for prolonged therapy.
• May mask symptoms of gastric cancer or serious gastrointestinal disease. Persistent or recurrent symptoms such as unexplained weight loss, difficulty swallowing, vomiting, or blood in stool require immediate medical evaluation.
• Drug interactions: Omeprazole may affect the metabolism of certain medicines (e.g., diazepam, phenytoin, warfarin, some antiretrovirals, clopidogrel, and others). Inform your doctor about all medications and supplements you are taking.
• Consult your doctor before use if pregnant or planning pregnancy. Use during pregnancy only if clearly needed and prescribed.
• Consult your doctor before use if breastfeeding. Omeprazole passes into breast milk; your doctor will weigh the benefits and potential risks.
• Not intended for self-diagnosis or long-term self-medication of recurrent heartburn without medical advice.
• Consult your doctor before use if you have liver disease, kidney disease, heart disease, are on a low-sodium diet, or are taking other regular medications.
• Keep out of reach of children.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.

Side Effects:

• Common side effects: Headache, abdominal pain, bloating, nausea, vomiting, constipation, diarrhea, flatulence, and dizziness. These are usually mild and transient.
• Less common side effects: Skin rash, itching, dry mouth, taste disturbances, fatigue, sleep disturbances, or joint pain.
• Serious side effects (seek immediate medical attention): Severe allergic reactions (swelling of face, lips, tongue or throat, difficulty breathing), severe skin reactions, persistent or severe diarrhea, signs of liver problems (yellowing of skin or eyes, dark urine), severe abdominal pain, or unexplained bruising.
• Long-term use side effects: Possible low magnesium levels (muscle cramps, irregular heartbeat, seizures), vitamin B12 deficiency, and increased fracture risk, especially in elderly or those on high-dose or prolonged therapy.
• If you experience any unusual or bothersome symptoms, stop using the product and consult your healthcare provider.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack in the original outer carton to protect from light. Do not store above 25°c unless otherwise stated on the package. Keep container tightly closed and keep out of reach of children. Do not use after the expiry date printed on the pack.

Specifications:

• Product type: Prescription gastric acid–suppressing medicine (proton pump inhibitor with antacid buffer).
• Active ingredients: Omeprazole 20 mg + sodium bicarbonate 1100 mg per capsule.
• Form: Capsule.
• Pack size: 14 capsules per pack.
• Intended users: Adults and adolescents as directed by a physician.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.