Downoprazol 40 Mg 14 Capsules

Downoprazol 40 Mg 14 Capsules

Description:

Downoprazol 40 mg 14 capsules is a prescription oral medicine containing omeprazole and sodium bicarbonate, used to reduce excessive stomach acid and relieve symptoms of acid-related disorders. It belongs to the class of proton pump inhibitors (PPIs) and is indicated for conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and other hyperacidity states. The added sodium bicarbonate helps protect omeprazole from stomach acid degradation and provides rapid antacid action for faster symptom relief. This product is intended for adult use under medical supervision.

Indications:

• Treatment of gastroesophageal reflux disease (GERD) and associated symptoms such as heartburn, acid regurgitation, and epigastric pain.
• Treatment and short-term healing of duodenal ulcers and gastric (stomach) ulcers caused by excess acid.
• Management of Zollinger–Ellison syndrome and other pathological hypersecretory conditions.
• Relief of acid-related dyspepsia (acid indigestion, burning sensation in the upper abdomen).
• Prevention and treatment of non-steroidal anti-inflammatory drug (NSAID)–associated gastric and duodenal ulcers, as directed by a physician.
• Adjunct in the prophylaxis of acid aspiration in high-risk patients during anesthesia, as prescribed by a doctor.

Active Ingredients / Key Components:

• Omeprazole – 40 mg per capsule (proton pump inhibitor that reduces gastric acid secretion).
• Sodium bicarbonate – 1100 mg per capsule (systemic antacid that neutralizes gastric acid and stabilizes omeprazole in the stomach).
• Other inactive ingredients/excipients: Not specified on the available source. Full excipient list is unavailable; please refer to the package insert.

Dosage & Administration / How to Use:

• Use exactly as prescribed by your physician. Do not exceed the recommended dose or duration.
• Typical adult dose for GERD and peptic ulcer disease: 40 mg omeprazole (one capsule) once daily, usually in the morning, or as directed by your doctor.
• For Zollinger–Ellison syndrome and other hypersecretory conditions, dosing may be higher and individualized by the physician.
• Take the capsule on an empty stomach, at least 30–60 minutes before a meal, with a full glass of water.
• Swallow the capsule whole; do not crush, chew, or open the capsule unless your doctor specifically instructs otherwise.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Duration of treatment varies: typically 2–8 weeks for ulcers or GERD, but may be longer for chronic conditions, as advised by your healthcare provider.
• Not recommended for self-medication in children; pediatric use must be strictly under medical supervision.

Clinical Benefits:

• Provides potent and sustained reduction of gastric acid secretion by irreversibly inhibiting the gastric proton pump (H+ / K+ ATPase) in parietal cells.
• Relieves heartburn, acid reflux, and upper abdominal pain associated with GERD and acid-related dyspepsia.
• Promotes healing of gastric and duodenal ulcers and helps prevent recurrence when used as directed.
• Helps protect the stomach lining in patients taking NSAIDs, reducing the risk of NSAID-induced ulcers.
• Combination with sodium bicarbonate offers faster onset of symptom relief through immediate acid neutralization.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to omeprazole, other proton pump inhibitors, sodium bicarbonate, or any component of the formulation.
• Do not use in patients with severe metabolic alkalosis or hypocalcemia, or in conditions where sodium intake must be strictly restricted, unless under close medical supervision.
• Use with caution in patients with severe liver impairment; dose adjustment and monitoring may be required.
• Long-term use of proton pump inhibitors may be associated with increased risk of bone fractures, vitamin B12 deficiency, hypomagnesemia, and Clostridioides difficile–associated diarrhea.
• May mask symptoms of gastric malignancy; in the presence of alarm symptoms (e.g., unintentional weight loss, persistent vomiting, dysphagia, gastrointestinal bleeding, anemia), malignancy should be excluded before starting therapy.
• Drug interactions: Omeprazole may alter blood levels of certain medicines such as diazepam, phenytoin, warfarin, clopidogrel, some antifungals, and antiretrovirals. Inform your doctor about all medications and supplements you are taking.
• Contains sodium bicarbonate; use cautiously in patients with heart failure, hypertension, renal impairment, or on sodium-restricted diets.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding. Use only if the potential benefit justifies the potential risk.
• Not intended for immediate relief of acute severe chest pain; if chest pain is accompanied by shortness of breath, sweating, or radiating pain, seek emergency medical attention.
• Consult your doctor before use if you have liver disease, kidney disease, osteoporosis, electrolyte disturbances, or are taking other long-term medications.
• Keep out of reach of children.

Side Effects:

• Common side effects may include headache, abdominal pain, nausea, vomiting, flatulence, diarrhea, or constipation.
• Less common side effects can include dizziness, fatigue, dry mouth, skin rash, pruritus, or edema.
• Serious but rare side effects: severe allergic reactions (angioedema, anaphylaxis), severe skin reactions (Stevens–Johnson syndrome, toxic epidermal necrolysis), liver dysfunction (jaundice, hepatitis), severe diarrhea or colitis, and significant electrolyte disturbances (especially low magnesium).
• Long-term use may be associated with increased risk of bone fractures, vitamin B12 deficiency, and low magnesium levels; your doctor may monitor these if prolonged therapy is needed.
• Stop use and seek immediate medical attention if you experience difficulty breathing, facial or throat swelling, severe skin rash, persistent diarrhea, or signs of gastrointestinal bleeding (black stools, blood in vomit).

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack in the original outer carton to protect from light. Do not store above 25°C unless otherwise stated on the package. Keep container tightly closed and keep out of reach of children. Do not use after the expiry date printed on the pack.

Specifications:

• Product type: Prescription medicine – proton pump inhibitor with antacid.
• Active ingredients: Omeprazole 40 mg + sodium bicarbonate 1100 mg per capsule.
• Form: Oral capsule.
• Pack size: 14 capsules per pack.
• Intended users: Adults and adolescents as directed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.