Erastapex Trio 20/5/12.5 Mg

Erastapex Trio 20/5/12.5 Mg

Description:

Erastapex Trio 20/5/12.5 mg is a prescription antihypertensive medicine used for the treatment and long‑term control of high blood pressure in adults. It combines three active ingredients—olmesartan, amlodipine, and hydrochlorothiazide—in one film‑coated tablet to provide comprehensive blood pressure reduction through complementary mechanisms. This triple therapy is typically used in patients whose blood pressure is not adequately controlled with dual therapy or single‑agent treatment. By helping to lower and maintain blood pressure within target ranges, Erastapex Trio supports cardiovascular health and helps reduce the risk of complications such as heart attack, stroke, and kidney damage when used as prescribed by a healthcare professional.

Indications:

• Treatment of essential (primary) hypertension in adults.
• Patients whose blood pressure is not adequately controlled with a combination of two antihypertensive agents (such as an angiotensin receptor blocker plus a calcium channel blocker, or an angiotensin receptor blocker plus a diuretic).
• Patients requiring a fixed‑dose triple combination to improve adherence and simplify their blood pressure treatment regimen.
• Helps reduce high blood pressure–related symptoms such as persistent headache, dizziness, and fatigue associated with uncontrolled hypertension (as evaluated by a physician).
• Supports long‑term cardiovascular risk reduction when used as part of a comprehensive hypertension management plan including diet, exercise, and lifestyle modification.

Active Ingredients / Key Components:

• Olmesartan medoxomil – 20 mg per film‑coated tablet (angiotensin II receptor blocker – ARB).
• Amlodipine besylate – equivalent to 5 mg amlodipine per film‑coated tablet (dihydropyridine calcium channel blocker).
• Hydrochlorothiazide – 12.5 mg per film‑coated tablet (thiazide diuretic).
• Other tablet excipients (such as fillers, binders, coating agents, and preservatives) are present but detailed composition is not available in the provided information.

Dosage & Administration / How to Use:

• Erastapex Trio 20/5/12.5 mg is for oral use only and must be taken exactly as prescribed by your doctor.
• Typical adult dose: one film‑coated tablet once daily, preferably at the same time each day. The exact dose and duration are determined by the prescribing physician based on blood pressure response and clinical status.
• May be taken with or without food. Swallow the tablet whole with a glass of water; do not crush, chew, or break the tablet unless advised by your doctor.
• If a dose is missed, take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed tablet.
• Do not stop taking Erastapex Trio suddenly without consulting your doctor, as abrupt discontinuation may lead to a rise in blood pressure.
• Regular monitoring of blood pressure, kidney function, and electrolytes (such as potassium and sodium) is recommended during treatment.
• Use in special populations (elderly patients, patients with kidney or liver impairment) requires careful dose adjustment and close medical supervision.

Clinical Benefits:

• Provides triple‑mechanism blood pressure control by combining an angiotensin II receptor blocker (olmesartan), a calcium channel blocker (amlodipine), and a thiazide diuretic (hydrochlorothiazide) in one tablet.
• Helps achieve and maintain target blood pressure in patients insufficiently controlled on dual therapy, supporting long‑term cardiovascular protection.
• Reduces peripheral vascular resistance and promotes vasodilation, improving blood flow and decreasing the workload on the heart.
• Enhances removal of excess salt and water through mild diuretic action, helping to reduce blood volume and blood pressure.
• Improves treatment adherence by simplifying complex antihypertensive regimens into a single daily dose.
• Supports reduction in the risk of hypertension‑related complications such as stroke, myocardial infarction, and kidney damage when used consistently as part of a comprehensive treatment plan.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to olmesartan, amlodipine, hydrochlorothiazide, other sulfonamide‑derived drugs, or any component of the formulation.
• Contraindicated during pregnancy. Drugs that act on the renin–angiotensin system (such as olmesartan) can cause injury and even death to the developing fetus. If pregnancy is detected, discontinue Erastapex Trio as soon as possible and contact your doctor immediately.
• Not recommended during breastfeeding unless clearly needed and only under strict medical supervision.
• Contraindicated in severe kidney impairment, anuria (inability to produce urine), or severe liver impairment unless specifically assessed and approved by a specialist.
• Use with caution in patients with renal artery stenosis, heart failure, aortic stenosis, hypertrophic cardiomyopathy, electrolyte imbalances (such as low potassium, low sodium), gout, diabetes, or a history of severe hypotension.
• May cause symptomatic hypotension, especially in volume‑depleted patients (e.g., those on high‑dose diuretics, low‑salt diet, or with diarrhea/vomiting). Start under medical supervision and report dizziness or fainting.
• Hydrochlorothiazide may increase uric acid and blood sugar levels; caution in patients with gout or diabetes.
• Amlodipine may cause peripheral edema (swelling of ankles or feet); inform your doctor if swelling becomes severe or persistent.
• Monitor kidney function and serum electrolytes periodically, especially in elderly patients or those on other medications affecting the renin–angiotensin–aldosterone system.
• Drug interactions: use with caution with other antihypertensives, potassium‑sparing diuretics, potassium supplements, lithium, NSAIDs, or certain heart medications. Inform your doctor and pharmacist about all medicines and supplements you are taking.
• May cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how the medicine affects you.
• Consult your doctor before use if pregnant, nursing, taking other medications, or if you have medical conditions such as kidney disease, liver disease, heart failure, diabetes, gout, or electrolyte disturbances.
• Keep out of reach of children.
• This product is a prescription antihypertensive medicine and must be used only under medical supervision.

Side Effects:

• Common side effects may include dizziness, headache, flushing, fatigue, palpitations, ankle or leg swelling (peripheral edema), nausea, abdominal discomfort, or mild gastrointestinal disturbances.
• Hydrochlorothiazide‑related effects may include increased urination, changes in electrolyte levels (low potassium, low sodium), increased uric acid (which may trigger gout), or slight increases in blood glucose or cholesterol.
• Less common but serious side effects may include severe hypotension (very low blood pressure), kidney function impairment, severe allergic reactions (rash, itching, swelling of face or tongue, difficulty breathing), chest pain, irregular heartbeat, or signs of liver problems (yellowing of skin or eyes, dark urine, severe abdominal pain).
• Very rare adverse reactions such as angioedema (swelling of the face, lips, tongue, or throat) may occur; seek emergency medical attention immediately if these appear.
• Contact your doctor promptly if you experience persistent dizziness, severe swelling, muscle weakness, irregular heartbeat, severe abdominal pain, or any unusual or worrying symptoms.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed in its original blister pack or carton to protect from moisture. Do not store above the temperature recommended on the package (typically below 25°c, if specified). Keep out of reach of children.

Specifications:

• Form: Film‑coated tablet.
• Strength per tablet: olmesartan medoxomil 20 mg + amlodipine 5 mg + hydrochlorothiazide 12.5 mg.
• Pack size: 30 film‑coated tablets (30 f.c. tabs) per box.
• Intended use: prescription antihypertensive medicine for adults.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.