Mepafuran 100 Mg 20 Capsules

Mepafuran 100 Mg 20 Capsules

Description:

Mepafuran 100 mg 20 capsules is a prescription antibacterial medicine containing nitrofurantoin, a nitrofuran derivative classified as a urinary germicide and miscellaneous antibiotic. It is used for the treatment and prevention of susceptible bacterial urinary tract infections (UTIs). Nitrofurantoin works locally in the urinary tract, reaching high concentrations in urine to inhibit the growth of bacteria that cause cystitis and lower urinary tract infections. This product is intended for adult and adolescent patients as directed by a healthcare professional.

Indications:

• Treatment of uncomplicated urinary tract infections (UTIs) caused by susceptible bacteria, such as acute cystitis.
• Management of recurrent lower urinary tract infections, when prescribed by a physician.
• Relief of urinary symptoms associated with bacterial infection, such as burning during urination, frequent urination, urgency, and lower abdominal discomfort, when due to susceptible organisms.
• Use as a urinary antiseptic in selected patients as recommended by a healthcare provider.

Active Ingredients / Key Components:

• Nitrofurantoin – 100 mg per capsule.
• Other inactive ingredients (excipients) are not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.). Full excipient list is unavailable and should be checked on the package insert.

Dosage & Administration / How to Use:

• Use exactly as prescribed by your doctor. Do not exceed the recommended dose or duration.
• Typical adult dosing regimens for nitrofurantoin (for general reference) often involve multiple daily doses with food; however, the exact dose, frequency, and duration for Mepafuran 100 mg must be determined by the prescribing physician.
• Swallow the capsule whole with a full glass of water. Do not crush or chew the capsules.
• It is generally recommended to take nitrofurantoin with food to increase bioavailability and improve gastrointestinal tolerance.
• Take doses at evenly spaced intervals throughout the day to maintain effective urinary concentrations.
• Continue the full course of therapy even if symptoms improve early, unless your doctor instructs you to stop.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Not recommended in patients with significantly reduced kidney function unless specifically advised by a specialist.

Clinical Benefits:

• Provides targeted antibacterial action within the urinary tract to control and eliminate susceptible bacteria.
• Helps relieve common UTI symptoms such as burning urination, frequency, and urgency when caused by sensitive organisms.
• Acts as a urinary germicide, achieving high concentrations in urine with relatively limited systemic exposure compared with some other antibiotics.
• May help reduce the risk of recurrent lower urinary tract infections when used under medical supervision.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity or allergy to nitrofurantoin or any component of the formulation.
• Generally contraindicated in patients with significantly impaired renal function due to reduced urinary excretion and increased risk of toxicity. Use only if clearly indicated and under strict medical supervision.
• Use with caution in patients with liver disease, glucose-6-phosphate dehydrogenase (G6PD) deficiency, anemia, diabetes, electrolyte imbalance, or vitamin B deficiency, as nitrofurantoin may exacerbate certain conditions.
• May cause pulmonary (lung) reactions, including acute or chronic pulmonary toxicity; discontinue and seek medical attention if you develop cough, chest pain, shortness of breath, or fever.
• May cause hepatic (liver) toxicity; discontinue and contact your doctor if you notice yellowing of the skin or eyes, dark urine, severe fatigue, or abdominal pain.
• Drug interactions: anticholinergic drugs may increase nitrofurantoin bioavailability by delaying gastric emptying; probenecid may decrease renal clearance and increase serum levels, raising toxicity risk; magnesium trisilicate may delay or decrease absorption; food increases bioavailability.
• May interfere with certain laboratory tests: can decrease serum glucose, elevate serum bilirubin and alkaline phosphatase, elevate urinary creatinine, and cause false-positive urinary glucose with Benedict’s reagent.
• Consult your doctor before use if pregnant or nursing. Nitrofurantoin is generally avoided at term (late pregnancy) and in neonates due to risk of hemolytic anemia.
• Not intended for use in infants unless specifically prescribed by a pediatric specialist.
• Do not use for viral infections (such as common cold or flu) or non-bacterial urinary symptoms.
• Consult your doctor before use if you are taking other medications, including probenecid, antacids containing magnesium trisilicate, or anticholinergic drugs.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects may include nausea, vomiting, loss of appetite, abdominal discomfort, diarrhea, and headache.
• Urine may become dark yellow or brown; this is usually harmless but should be discussed with your doctor if you are concerned.
• Allergic reactions may occur, including rash, itching, hives, or swelling. Discontinue and seek medical advice if these appear.
• Serious but less common side effects can include pulmonary reactions (shortness of breath, cough, chest pain), peripheral neuropathy (numbness, tingling, or weakness in hands or feet), liver dysfunction (jaundice, dark urine, severe fatigue), and blood disorders such as hemolytic anemia, particularly in G6PD-deficient patients.
• Stop taking the medicine and seek urgent medical attention if you experience difficulty breathing, severe skin reactions, persistent fever, unexplained bruising or bleeding, or severe abdominal pain.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Store at or below the temperature recommended on the package insert (exact temperature range is not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.) and should be checked on the product packaging).

Specifications:

• Form: Capsules.
• Strength: 100 mg nitrofurantoin per capsule.
• Pack size: 20 capsules per pack.
• Intended use: Prescription antibacterial medicine for urinary tract infections, as directed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.