Mepafuran 50 Mg 20 Cap

Mepafuran 50 Mg 20 Cap

Description:

Mepafuran 50 mg 20 cap is a prescription oral antibiotic medicine containing nitrofurantoin, a nitrofuran derivative urinary antiseptic. It is specifically used for the treatment and prevention of uncomplicated urinary tract infections (UTIs) caused by susceptible bacteria. Mepafuran acts locally in the urine to inhibit bacterial growth and damage bacterial dna, helping relieve symptoms such as burning urination, frequent urination, and lower abdominal discomfort. This product is intended for use under medical supervision only.

Indications:

• Treatment of acute uncomplicated urinary tract infections (UTIs), such as cystitis, caused by susceptible strains of bacteria.
• Prevention and prophylaxis of recurrent urinary tract infections in patients as directed by a physician.
• Relief of UTI-associated symptoms including dysuria (burning during urination), urinary frequency, urgency, and suprapubic discomfort, as part of the overall treatment of the infection.

Active Ingredients / Key Components:

• Nitrofurantoin – 50 mg per capsule.
• Other inactive ingredients/excipients: not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.) (full excipient list not available).

Dosage & Administration / How to Use:

• Use only as prescribed by a physician and follow the instructions on the product packaging.
• Typical adult dosing for uncomplicated UTI is commonly multiple times daily; the exact dose, frequency, and duration must be determined by the treating doctor based on the type and severity of infection and kidney function. Specific dosing regimen is not provided in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.).
• Capsules are usually taken by mouth with food or milk to improve absorption and reduce gastrointestinal side effects. Food increases the bioavailability of nitrofurantoin.
• Swallow the capsule whole with a sufficient amount of water. Do not crush or chew unless your doctor or pharmacist specifically advises otherwise.
• Take doses at evenly spaced intervals throughout the day to maintain effective antibiotic levels in the urine.
• Complete the full course of therapy even if symptoms improve early, to reduce the risk of recurrence and antibiotic resistance.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Do not use in children or in patients with significantly reduced kidney function unless specifically directed by a specialist.

Clinical Benefits:

• Targets urinary pathogens directly in the urinary tract, helping to clear bacterial infections effectively.
• Helps relieve common UTI symptoms such as burning urination, urgency, and frequent urination as the infection resolves.
• Acts as a bacteriostatic agent by forming active metabolites that damage bacterial dna, reducing bacterial growth and spread.
• Useful for both treatment and prevention of recurrent urinary tract infections when prescribed for prophylaxis.

Warnings & Contraindications:

• Do not use Mepafuran if you are allergic to nitrofurantoin or any other nitrofuran derivatives, or to any component of the formulation.
• Contraindicated in patients with significantly impaired renal function (severe kidney disease) due to risk of toxicity and reduced urinary concentrations.
• Generally not recommended in late pregnancy (especially at term), in neonates, or in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency due to risk of hemolytic anemia.
• Use with caution in patients with liver disease, pulmonary disease, anemia, diabetes, or electrolyte imbalance, and in elderly patients. Regular monitoring may be required.
• Drug interactions: anticholinergic drugs may increase nitrofurantoin bioavailability by delaying gastric emptying; probenecid can decrease renal clearance and increase serum levels, raising toxicity risk; magnesium trisilicate may delay or decrease absorption; food increases bioavailability.
• May interfere with certain laboratory tests: can decrease serum glucose, increase serum bilirubin and alkaline phosphatase, elevate urinary creatinine, and cause false-positive urinary glucose with Benedict's reagent.
• Consult your doctor before use if pregnant, nursing, planning pregnancy, taking other medications, or if you have kidney disease, liver disease, lung disease, G6PD deficiency, anemia, or chronic illnesses such as diabetes.
• Do not use this medicine for viral infections such as colds or flu.
• Not intended to diagnose, treat, cure, or prevent any disease without medical supervision.
• Keep out of reach of children.
• Do not exceed the prescribed dose or duration. Prolonged use may increase the risk of side effects, including lung or liver toxicity.

Side Effects:

• Common side effects may include nausea, vomiting, loss of appetite, abdominal discomfort, and diarrhea, especially if taken on an empty stomach.
• Other possible effects: headache, dizziness, drowsiness, or mild skin rash.
• Serious side effects (seek immediate medical attention): difficulty breathing, persistent cough, chest pain, fever, chills (possible pulmonary reaction); yellowing of the skin or eyes, dark urine, severe fatigue (possible liver problems); numbness, tingling, or weakness in hands or feet (possible peripheral neuropathy); severe allergic reactions such as swelling of face, lips, tongue, or throat, or severe skin rash.
• Hemolytic anemia may occur in patients with G6PD deficiency, neonates, or during late pregnancy.
• If you experience any unusual or persistent symptoms, stop the medication and contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the container tightly closed and store at room temperature unless otherwise specified on the package. Do not use after the expiry date printed on the pack. Keep out of reach of children.

Specifications:

• Active ingredient: nitrofurantoin 50 mg per capsule.
• Form: hard gelatin capsule for oral use.
• Pack size: 20 capsules per pack.
• Intended use: prescription systemic antibiotic for urinary tract infections.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.