Mestinon 60 mg - Pyridostigmine Bromide Dragées (150 Tablets)

Mestinon 60 Mg 150 Tablets

Description:

Mestinon 60 mg 150 tablets is a prescription oral medicine containing pyridostigmine bromide, a reversible cholinesterase inhibitor used primarily in the management of myasthenia gravis. By improving neuromuscular transmission, it helps reduce muscle weakness and fatigue, supporting better muscle strength and daily function in affected patients. Mestinon is classified as a systemic neuromuscular medication and should be used strictly under medical supervision.

Indications:

• Treatment of myasthenia gravis, including generalized and ocular forms, to improve muscle strength and reduce fatigable weakness.
• Helps relieve symptoms such as drooping eyelids, difficulty swallowing, chewing or speaking, and generalized muscle fatigue associated with myasthenia gravis.
• May be used (under specialist supervision) as an adjunct to reverse non-depolarizing neuromuscular blocking agents after surgery (off-label in some settings; follow physician guidance).

Active Ingredients / Key Components:

• Pyridostigmine bromide – 60 mg per tablet.
• Inactive ingredients/excipients: Full excipient list is not available in the provided information; refer to the package leaflet for complete details.

Dosage & Administration / How to Use:

• Use only as prescribed by a neurologist or healthcare professional experienced in treating myasthenia gravis.
• Typical adult dosing for myasthenia gravis is individualized; doses are divided throughout the day according to symptom control and duration of effect. The exact dose, frequency, and schedule must be determined by the treating physician.
• Tablets are usually taken orally with water. They may be taken with or without food; taking with food can help reduce gastrointestinal side effects in some patients.
• Do not change the dose, dosing interval, or discontinue the medicine without consulting your doctor, as abrupt changes may worsen myasthenic symptoms.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• In patients with renal impairment, dose adjustment is often required; this must be done by a physician.
• Always follow the instructions on the prescription label and the patient information leaflet provided with the pack.

Clinical Benefits:

• Improves neuromuscular transmission by inhibiting acetylcholinesterase, increasing acetylcholine availability at the neuromuscular junction.
• Helps reduce muscle weakness and fatigue in patients with myasthenia gravis, supporting better mobility and daily activity performance.
• May improve specific symptoms such as ptosis (drooping eyelids), difficulty swallowing, chewing, and speaking, thereby enhancing quality of life.
• Provides a reversible and titratable therapeutic option with a longer duration of action than neostigmine in many patients.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to pyridostigmine bromide or any component of the formulation.
• Use with extreme caution in patients with mechanical intestinal or urinary obstruction, as increased smooth muscle activity may worsen obstruction.
• Caution in patients with bronchial asthma, chronic obstructive pulmonary disease (copd), bradycardia, cardiac arrhythmias, recent coronary artery disease, hypotension, peptic ulcer disease, epilepsy, or Parkinson’s disease.
• Overdosage may cause cholinergic crisis, which can mimic or worsen myasthenic symptoms and may be life-threatening. Immediate medical attention is required if severe muscle weakness, breathing difficulty, or excessive secretions occur.
• Use in pregnancy and breastfeeding only if clearly needed and under strict medical supervision. Discuss risks and benefits with your doctor.
• May interact with other medications such as beta-blockers, other cholinesterase inhibitors, anticholinergic drugs, neuromuscular blocking agents, and certain antibiotics. Inform your doctor about all medicines and supplements you are taking.
• Consult your doctor before use if pregnant, nursing, taking other medications, or have medical conditions including heart disease, respiratory disease, kidney impairment, gastrointestinal disorders, or urinary obstruction.
• Not intended for self-diagnosis or self-treatment. Use only under prescription and regular medical follow-up.
• Keep out of reach of children.

Side Effects:

• Common side effects may include nausea, vomiting, diarrhea, abdominal cramps, increased salivation, increased sweating, increased bronchial secretions, muscle cramps, and mild bradycardia (slow heart rate).
• Other possible effects: urinary urgency, increased tearing, miosis (small pupils), and flushing.
• Signs of cholinergic excess or cholinergic crisis (medical emergency) include severe muscle weakness, difficulty breathing, extreme salivation, sweating, slow heart rate, severe abdominal cramps, and diarrhea. Seek immediate medical attention if these occur.
• Allergic reactions such as rash, itching, swelling of the face, lips, or tongue, or difficulty breathing require urgent medical care.
• If any side effects are severe, persistent, or unexpected, contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date stated on the packaging. Store at or below the temperature specified on the product carton or leaflet (exact temperature range not provided; refer to pack for details).

Specifications:

• Product type: Prescription medicine – oral neuromuscular agent.
• Strength: 60 mg pyridostigmine bromide per tablet.
• Form: Tablet.
• Pack size: 150 tablets per pack.
• Intended use: Adult and adolescent patients as directed by a physician for the treatment of myasthenia gravis.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.