No-Uric 300 Mg Tablets
Description:
No-Uric 300 mg tablets are a prescription oral medicine containing allopurinol, a xanthine oxidase inhibitor used to lower high uric acid levels in the blood. It is primarily indicated for the long-term management of chronic gout and hyperuricemia, and for the prevention of uric acid kidney stones and uric acid nephropathy, especially in patients receiving cancer chemotherapy or radiation. By reducing the production of uric acid, No-Uric 300 mg tablets help prevent gout attacks, joint damage, and kidney complications associated with elevated uric acid levels.
Indications:
- Chronic gout with hyperuricemia (elevated uric acid levels in the blood).
- Primary hyperuricemia associated with gouty arthritis and recurrent gout attacks.
- Secondary hyperuricemia due to conditions such as myeloid metaplasia, radiation therapy, and cancer chemotherapy (e.g., tumor lysis syndrome risk).
- Hyperuricemia induced by certain medicines such as thiazide diuretics.
- Prevention of uric acid nephropathy and uric acid kidney stone formation in high-risk patients.
- Adjunctive treatment in patients with recurrent uric acid renal stones where dietary and other measures are insufficient.
Active Ingredients / Key Components:
- Allopurinol – 300 mg per tablet (xanthine oxidase inhibitor that reduces uric acid production).
- Excipients: Other inactive ingredients (tablet base, binders, fillers, coating agents, etc.) – exact composition and concentrations , please check the product leaflet or the manufacturer’s official website.
Dosage & Administration / How to Use:
- Use No-Uric 300 mg tablets exactly as prescribed by your physician. Dosage must be individualized based on serum uric acid level, kidney function, and clinical response.
- Typical adult dose for chronic gout and hyperuricemia: often initiated at a lower dose (e.g., 100 mg daily) and gradually increased. A 300 mg daily dose is commonly used as a maintenance dose in many adults, but may be adjusted higher or lower as directed by the doctor.
- In patients with impaired kidney function, lower doses or extended dosing intervals are usually required. Dose adjustment must be guided by a healthcare professional.
- Tablets are usually taken once daily after food with a full glass of water to minimize gastrointestinal discomfort. In some cases, the daily dose may be divided as advised by the physician.
- Maintain adequate hydration (unless contraindicated) to help reduce the risk of kidney stone formation; your doctor may recommend increased fluid intake.
- Do not use allopurinol to treat an acute gout attack. It is for long-term control of uric acid. If a gout attack occurs while on treatment, continue taking No-Uric unless your doctor advises otherwise and use appropriate anti-inflammatory medicines for the attack.
- Take the tablet at the same time each day to maintain a consistent level in your blood.
- If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed dose.
- Do not stop taking No-Uric 300 mg tablets without consulting your doctor, even if symptoms improve, as stopping abruptly may cause uric acid levels to rise again.
Clinical Benefits:
- Helps reduce serum uric acid levels by inhibiting xanthine oxidase, the key enzyme responsible for uric acid production.
- Prevents recurrent gout attacks and reduces the frequency and severity of gout flares over time when used regularly.
- Helps prevent the formation of uric acid crystals and tophi in joints and tissues, supporting joint health and mobility.
- Reduces the risk of uric acid kidney stones and uric acid nephropathy, especially in patients undergoing cancer chemotherapy or with high cell turnover.
- Supports long-term management of chronic hyperuricemia when combined with lifestyle measures such as diet and weight control.
Warnings & Contraindications:
- Contraindicated in patients with known hypersensitivity to allopurinol or any component of the formulation.
- Contraindicated in acute gout attacks; it should not be started during an active flare. Treatment is usually initiated after the acute attack has completely subsided.
- Contraindicated in patients with hemochromatosis, as per product information, due to potential effects on iron metabolism.
- Serious and sometimes life-threatening skin reactions (including Stevens–Johnson syndrome and toxic epidermal necrolysis) have been reported with allopurinol. Stop the medicine and seek immediate medical attention if rash, blistering, peeling skin, mouth ulcers, fever, or flu-like symptoms occur.
- Use with caution in patients with kidney or liver impairment; dose adjustment and close monitoring are required.
- Use with caution in patients with hypertension, heart disease, or those taking diuretics or ACE inhibitors, as the risk of adverse reactions may be increased.
- Drug interactions: allopurinol may interact with azathioprine, 6-mercaptopurine, warfarin, theophylline, certain antibiotics, and other medicines. Inform your doctor about all medicines and supplements you are taking.
- Consult your doctor before use if pregnant or planning pregnancy. Allopurinol should be used in pregnancy only if clearly needed and prescribed by a physician.
- If breastfeeding, consult your doctor before use, as allopurinol and its metabolites may be excreted in breast milk.
- Patients with a history of kidney stones or chronic kidney disease should be monitored regularly (renal function tests, uric acid levels).
- May cause drowsiness or dizziness in some individuals; if affected, do not drive or operate machinery until you know how the medicine affects you.
- Not intended to diagnose, treat, cure, or prevent any disease without medical supervision. Use only under the guidance of a qualified healthcare professional.
- Keep out of reach of children.
Side Effects:
- Common side effects: gastrointestinal upset (nausea, vomiting, diarrhea), abdominal pain, loss of appetite, and mild skin rash or itching.
- Less common side effects: headache, dizziness, drowsiness, changes in taste, and mild elevation of liver enzymes.
- Serious side effects (seek immediate medical attention): severe skin reactions (Stevens–Johnson syndrome, toxic epidermal necrolysis), widespread rash with blistering or peeling, fever, swollen lymph nodes, mouth ulcers, yellowing of the skin or eyes (jaundice), dark urine, severe abdominal pain, blood disorders (unusual bruising or bleeding, persistent sore throat, infections), or signs of severe allergic reaction (swelling of face, lips, tongue, or throat, difficulty breathing).
- If you experience any unusual or persistent symptoms while taking No-Uric 300 mg tablets, contact your doctor or pharmacist promptly.
Storage Instructions:
Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.
Specifications:
- Strength: 300 mg allopurinol per tablet.
- Form: Oral tablets.
- Pack size: 20 tablets per pack (as per available product information "20 tabs").
- Intended use: Prescription medicine for adults and suitable adolescents as directed by a physician for the management of hyperuricemia and gout.
Disclaimer: All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.
