Prontogest 200 Mg 30 Suppository

Prontogest 200 Mg 30 Suppository

Description:

Prontogest 200 mg suppositories are a prescription hormonal medicine containing natural micronized progesterone, designed for vaginal or rectal use. It is used primarily for progesterone supplementation or replacement in women with progesterone deficiency, especially in assisted reproductive technology (ART) protocols, and for various gynecological and hormonal conditions. By providing exogenous progesterone, Prontogest supports the luteal phase, stabilizes the endometrium, and helps regulate the menstrual cycle and uterine bleeding patterns under medical supervision.

Indications:

• Progesterone supplementation or replacement as part of assisted reproductive technology (ART) treatment in infertile women with documented or suspected progesterone deficiency.
• Treatment of secondary amenorrhea (absence of menstruation in women who previously had regular cycles) due to progesterone deficiency, as prescribed by a gynecologist.
• Reduction of the incidence of endometrial hyperplasia in postmenopausal women receiving estrogen replacement therapy, thereby lowering the associated risk of endometrial carcinoma.
• Treatment of abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology (such as fibroids, uterine cancer, or other structural uterine disease).
• Support of the luteal phase in selected fertility treatment protocols, as directed by a fertility specialist.

Active Ingredients / Key Components:

• Progesterone (micronized) – 200 mg per suppository.
• Excipients/base components: Specific suppository base and inactive ingredients are not listed in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.); full excipient details are unavailable and should be checked on the package insert.

Dosage & Administration / How to Use:

• Prontogest 200 mg is for vaginal or rectal use only. Do not take by mouth.
• Recommended dose and frequency are individualized by the treating physician based on indication (ART support, secondary amenorrhea, abnormal uterine bleeding, or use with estrogen therapy).
• For ART and luteal phase support: Often used once or multiple times daily as prescribed, starting after ovulation or embryo transfer and continued for the duration recommended by the fertility specialist.
• For secondary amenorrhea or abnormal uterine bleeding: Typically given in cyclic regimens (e.g., for several days each cycle) according to the gynecologist’s instructions.
• For use with estrogen replacement therapy: Administered for a defined number of days each cycle to protect the endometrium; follow the schedule provided by your doctor.
• Administration technique (vaginal): Wash and dry hands, remove the suppository from its blister, gently insert deep into the vagina while lying on your back or in a comfortable position, preferably at bedtime to reduce leakage.
• Administration technique (rectal): Wash and dry hands, if needed moisten the suppository with a little water, gently insert into the rectum beyond the sphincter, preferably after bowel evacuation.
• Use at the same time(s) each day to maintain stable hormone levels.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one. Consult your doctor if multiple doses are missed, especially during ART cycles.
• Always follow your doctor’s dosing schedule and do not change the dose or duration without medical advice.

Clinical Benefits:

• Provides reliable progesterone supplementation in women undergoing assisted reproductive technology (ART), helping support implantation and early pregnancy maintenance when indicated.
• Helps restore a more normal menstrual pattern in cases of secondary amenorrhea related to progesterone deficiency.
• Reduces the risk of estrogen-induced endometrial hyperplasia and the associated risk of endometrial carcinoma in postmenopausal women on estrogen replacement therapy.
• Stabilizes the endometrial lining and helps control abnormal uterine bleeding due to hormonal imbalance when no structural uterine pathology is present.

Warnings & Contraindications:

• Use only under the supervision of a qualified healthcare professional, especially in fertility treatment or hormone replacement therapy.
• Contraindicated in known or suspected pregnancy unless specifically prescribed for luteal support in ART or pregnancy support by a specialist.
• Contraindicated in known or suspected breast cancer, estrogen- or progesterone-dependent tumors, undiagnosed vaginal bleeding, active or history of thromboembolic disorders (e.g., deep vein thrombosis, pulmonary embolism), severe liver dysfunction or liver disease, and known hypersensitivity to progesterone or any component of the product.
• Use with caution in patients with a history of depression, migraine, epilepsy, asthma, cardiovascular disease, or renal impairment; close medical monitoring may be required.
• May cause drowsiness or dizziness; caution is advised when driving or operating machinery until you know how the medicine affects you.
• Vaginal use may be associated with local irritation or discharge; if symptoms are severe or persistent, contact your doctor.
• Consult your doctor before use if pregnant, planning pregnancy (outside ART protocols), or breastfeeding. Progesterone use in pregnancy must be strictly guided by a specialist.
• Inform your doctor about all other medicines you are taking, including hormonal therapies, anticoagulants, and herbal supplements, to avoid potential interactions.
• Not intended to diagnose, treat, cure, or prevent any disease without appropriate medical evaluation and prescription.
• Keep out of reach of children.

Side Effects:

• Common side effects may include headache, dizziness, drowsiness, breast tenderness, mood changes, abdominal discomfort, bloating, or vaginal/rectal irritation and discharge at the site of application.
• Less common side effects can include nausea, vomiting, changes in libido, fluid retention, or weight changes.
• Serious side effects (seek immediate medical attention) may include signs of thromboembolism such as sudden shortness of breath, chest pain, coughing blood, severe headache, visual disturbances, unilateral leg swelling or pain, or sudden weakness or numbness.
• Allergic reactions (rash, itching, swelling of face/lips/tongue, severe dizziness, difficulty breathing) require urgent medical care and discontinuation of the product.
• If you experience persistent abnormal vaginal bleeding, severe abdominal pain, jaundice (yellowing of the skin or eyes), or marked mood changes, contact your doctor promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and sources of heat. Keep the suppositories in their original blister pack until use to protect from moisture and contamination. Do not use after the expiry date printed on the pack. Keep out of reach of children.

Specifications:

• Form: Vaginal or rectal suppositories (pessaries).
• Strength: 200 mg progesterone per suppository.
• Pack size: 30 suppositories per pack.
• Route of administration: Vaginal or rectal, as directed by the physician.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.