Spaniela mr 35mg 30

Spaniela mr 35mg 30

Description:

Spaniela mr 35mg 30 f.c. tablets is a prescription cardiovascular medicine containing trimetazidine in modified-release (mr) form. It is an anti-ischemic (anti-anginal) agent used as an adjunct treatment in patients with stable angina pectoris to improve myocardial (heart muscle) tolerance to ischemia. By optimizing cardiac energy metabolism at the cellular level, Spaniela mr helps reduce the frequency of angina attacks and enhance exercise tolerance when used alongside standard therapies such as beta-blockers, calcium channel blockers, or nitrates.

Indications:

• Adjunctive therapy in the management of stable angina pectoris in adults.
• Reduction in frequency and severity of anginal attacks when combined with first-line anti-anginal treatments.
• Improvement of exercise tolerance in patients with chronic ischemic heart disease.
• Supportive cytoprotective effect on myocardial cells during episodes of reduced blood flow (ischemia).

Active Ingredients / Key Components:

• Trimetazidine dihydrochloride – 35 mg per modified-release film-coated tablet.
• Other excipients: film-coating agents, fillers, and stabilizers (exact excipient list and concentrations , please check the product leaflet or the manufacturer’s official website; please refer to the official package insert for full details).

Dosage & Administration / How to Use:

• Adults: The commonly used dose of trimetazidine mr is 35 mg twice daily (morning and evening), taken with meals. However, the exact dose and regimen must be determined by the treating physician based on individual clinical status and concomitant medications.
• Swallow the modified-release film-coated tablet whole with a sufficient amount of water. Do not crush, chew, or break the tablet to preserve the controlled-release profile.
• Use Spaniela mr as adjunctive therapy; it is not intended as first-line monotherapy for unstable angina or acute coronary syndromes.
• In patients with moderate renal impairment or in elderly patients, dose adjustment and careful monitoring may be required; follow physician instructions strictly.
• If a dose is missed, take it as soon as you remember unless it is nearly time for the next dose. Do not double the dose to make up for a missed tablet.
• Always follow your cardiologist’s or healthcare provider’s directions and do not change the dose or discontinue treatment without medical advice.

Clinical Benefits:

• Helps reduce the frequency and intensity of angina attacks by improving myocardial energy efficiency.
• Enhances exercise tolerance and physical performance in patients with stable ischemic heart disease.
• Provides cytoprotective effects by limiting intracellular acidosis and reducing sodium and calcium overload in ischemic cardiac cells.
• Protects myocardial cell membranes against oxidative stress and free radical-induced damage.
• Acts via a non-haemodynamic mechanism, without significant effects on heart rate or blood pressure, making it a useful adjunct to standard hemodynamic therapies.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to trimetazidine or any component of the formulation.
• Not indicated for the treatment of acute coronary syndromes (such as myocardial infarction) or unstable angina, and must not be used as initial therapy for these conditions.
• Use with caution in patients with moderate renal impairment; dose adjustment and regular monitoring may be necessary. Not recommended in severe renal impairment (creatinine clearance < 30 ml/min) unless specifically advised by a specialist.
• Cases of movement disorders (parkinsonian symptoms, tremor, gait instability, restless leg syndrome) have been reported with trimetazidine; treatment should be discontinued if such symptoms occur.
• May cause dizziness or drowsiness in some patients; caution is advised when driving or operating machinery until individual response is known.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding; safety data in these populations are limited.
• Consult your doctor before use if you have Parkinson’s disease, severe kidney disease, or other serious neurological or cardiovascular conditions.
• Not intended to diagnose, treat, cure, or prevent any disease on its own; it is used as part of a comprehensive cardiovascular treatment plan as prescribed by a physician.
• Keep out of reach of children.

Side Effects:

• Common side effects may include gastrointestinal disturbances such as nausea, vomiting, abdominal pain, indigestion, or diarrhea.
• Other possible effects: headache, dizziness, fatigue, or rash.
• Less common but important: movement disorders including tremor, rigidity, akinesia, gait disturbances, or restless leg syndrome; these usually resolve after discontinuation of treatment. If any of these occur, contact your doctor immediately.
• Allergic reactions (such as swelling of the face, lips, tongue, or throat, severe rash, or difficulty breathing) are rare but require urgent medical attention.
• If you experience any unusual or severe symptoms, stop taking the medicine and seek medical advice promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date printed on the pack. Store at or below the temperature specified in the official package insert (exact temperature range not available in the provided information).

Specifications:

• Product type: Prescription cardiovascular medicine (anti-anginal, anti-ischemic).
• Strength: 35 mg trimetazidine per modified-release film-coated tablet.
• Form: Film-coated modified-release tablet.
• Pack size: 30 tablets per pack.
• Intended use: Adult patients with stable angina pectoris as adjunctive therapy, under medical supervision.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.