Tegretol Cr 400 Mg 20 Tablets

Tegretol Cr 400 Mg 20 Tablets

Description:

Tegretol CR 400 mg is a prescription anticonvulsant medicine containing carbamazepine in a controlled-release (CR) tablet form. It is primarily used for the treatment of epilepsy, trigeminal neuralgia, and certain mood disorders such as bipolar disorder. The controlled-release formulation provides a gradual and sustained release of carbamazepine over time, helping maintain stable blood levels, reduce seizure frequency, and improve symptom control with fewer daily doses. This product is intended for use under medical supervision only.

Indications:

• Treatment of epilepsy, including generalized tonic-clonic seizures (grand mal epilepsy).
• Management of partial seizures, including complex partial (psychomotor) seizures.
• Treatment of trigeminal neuralgia (severe facial nerve pain).
• Adjunctive treatment of manic episodes and maintenance therapy in bipolar (manic-depressive) disorder, as prescribed by a psychiatrist.
• Helps reduce seizure frequency and severity in patients diagnosed with epilepsy.
• Relief of recurrent, sharp, stabbing facial pain associated with trigeminal neuralgia.

Active Ingredients / Key Components:

• Carbamazepine – 400 mg per controlled-release tablet.
• Other excipients: controlled-release matrix and tablet core/shell components (full excipient list and exact concentrations , please check the product leaflet or the manufacturer’s official website; please refer to the official package leaflet).

Dosage & Administration / How to Use:

• Use only as prescribed by a physician experienced in the treatment of epilepsy, neuropathic pain, or mood disorders.
• Typical adult dosing for epilepsy or trigeminal neuralgia is individualized; the doctor will usually start with a low dose and gradually increase based on response and tolerability. A 400 mg controlled-release tablet may be used once or twice daily as part of the total daily dose, according to medical advice.
• For bipolar disorder or acute mania, dosing and duration are determined strictly by the treating psychiatrist.
• Swallow the tablets whole with a glass of water. Do not crush, chew, or break the controlled-release tablets, as this may alter the release profile and increase side effects.
• Can be taken with or after food to reduce gastrointestinal discomfort, unless otherwise directed by your doctor.
• Take the medicine at the same time(s) each day to maintain stable blood levels.
• If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Do not stop taking Tegretol CR suddenly without consulting your doctor, as abrupt discontinuation may increase seizure risk or cause symptom relapse.

Clinical Benefits:

• Helps control generalized tonic-clonic and partial seizures by stabilizing neuronal activity in the brain.
• Provides effective relief of trigeminal neuralgia by reducing abnormal nerve firing and pain signals.
• Supports mood stabilization in bipolar disorder, helping to reduce manic episodes when used under psychiatric supervision.
• Controlled-release formulation offers more stable blood levels of carbamazepine, which may improve tolerability and reduce fluctuations in symptom control.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to carbamazepine, tricyclic antidepressants, or any component of the formulation.
• Contraindicated in patients with a history of bone marrow depression.
• Contraindicated in patients with atrioventricular (AV) block or a history of serious cardiac conduction disorders, unless strictly supervised.
• Do not use in combination with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOI therapy.
• Use with extreme caution in patients with liver disease, kidney impairment, heart disease, glaucoma, or blood disorders; regular monitoring may be required.
• May cause serious skin reactions (e.g., Stevens–Johnson syndrome, toxic epidermal necrolysis), especially in certain genetic populations; seek immediate medical attention if rash, blistering, or mucosal lesions occur.
• May cause hyponatremia (low sodium levels); caution in elderly patients and those on diuretics or with heart failure.
• Can cause dizziness, drowsiness, and blurred vision; avoid driving, operating machinery, or performing tasks requiring alertness until you know how the medicine affects you.
• Carbamazepine interacts with many medicines (e.g., certain antibiotics, antifungals, anticoagulants, other antiepileptics, oral contraceptives); always inform your doctor and pharmacist about all medications and supplements you are taking.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding. Carbamazepine may affect fetal development and passes into breast milk; risk–benefit assessment is essential.
• Alcohol may increase drowsiness and affect seizure control; avoid or limit alcohol consumption.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects may include dizziness, drowsiness, fatigue, headache, nausea, vomiting, dry mouth, unsteadiness, or blurred/double vision.
• Gastrointestinal disturbances such as abdominal pain or constipation may occur.
• Blood-related effects (e.g., leukopenia, thrombocytopenia, anemia) can occur; your doctor may order regular blood tests. Seek medical help if you develop unexplained fever, sore throat, easy bruising, or bleeding.
• Serious skin reactions (Stevens–Johnson syndrome, toxic epidermal necrolysis) are rare but potentially life-threatening; discontinue use and seek urgent medical attention if rash, peeling skin, mouth ulcers, or eye irritation appear.
• Allergic reactions such as swelling of the face, lips, tongue, or throat, severe dizziness, or difficulty breathing require immediate emergency care.
• Mood changes, confusion, agitation, or suicidal thoughts have been reported with antiepileptic drugs; contact your doctor immediately if such symptoms occur.
• This is not a complete list of side effects. Always read the patient information leaflet and consult your doctor or pharmacist for further guidance.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.

Specifications:

• Form: Controlled-release film-coated tablets.
• Strength: 400 mg carbamazepine per tablet.
• Pack size: 20 tablets per pack.
• Route of administration: Oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.