Xilone Forte Syrup

Xilone Forte Syrup

Description:

Xilone Forte 15 mg/5 ml Syrup 100 ml is a prescription oral corticosteroid medicine containing prednisolone, a systemic synthetic glucocorticoid with potent anti-inflammatory and immunosuppressive effects. It is used to treat a wide range of inflammatory and allergic conditions, helping to reduce swelling, redness, itching, and immune overactivity. Xilone Forte Syrup is especially suitable for patients who require a liquid form of prednisolone for easier swallowing and accurate dose adjustment under medical supervision.

Indications:

• Treatment of acute and chronic inflammatory conditions responsive to systemic corticosteroids (as prescribed by a physician).
• Management of severe allergic reactions such as drug hypersensitivity reactions, severe allergic rhinitis, and severe atopic or contact dermatitis (as directed by a doctor).
• Adjunctive therapy in bronchial asthma and other steroid-responsive respiratory conditions to reduce airway inflammation and bronchial hyperreactivity.
• Supportive treatment in certain autoimmune and immunological disorders where glucocorticoids are indicated (e.g., some collagen and rheumatic diseases), according to specialist guidance.
• Management of inflammatory conditions of various organs (e.g., gastrointestinal, hematologic, or neurologic disorders) where systemic prednisolone is indicated.
• Any other condition where the prescribing physician considers systemic prednisolone therapy necessary.

Active Ingredients / Key Components:

• Prednisolone – 15 mg per 5 ml oral syrup (concentration as stated: 15 mg/5 ml).
• Excipients: The full list of inactive ingredients (sweeteners, flavoring agents, stabilizers, preservatives, and solvents) is not available in the provided information. Please refer to the product package insert for a complete excipient list.

Dosage & Administration / How to Use:

• Xilone Forte Syrup is for oral use only and must be taken exactly as prescribed by your doctor.
• Typical dosage: The dose, frequency, and duration are individualized based on the disease being treated, its severity, and patient factors (age, weight, and response). Follow your physician’s instructions carefully.
• Measurement: Use a calibrated measuring spoon, oral syringe, or dosing cup to ensure accurate dosing. Do not use a household teaspoon.
• With or without food: Prednisolone is often recommended to be taken with food or milk to help reduce gastric irritation. Follow your doctor’s or pharmacist’s advice.
• Timing: If prescribed once daily, it is commonly taken in the morning to mimic the body’s natural cortisol rhythm, unless your doctor advises otherwise.
• Tapering: Do not stop taking Xilone Forte Syrup suddenly if you have been using it for more than a few days or at high doses. Your doctor may gradually reduce the dose (tapering) to avoid adrenal insufficiency and withdrawal symptoms.
• Missed dose: If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one; consult your doctor if unsure.
• Children: Pediatric dosing must be strictly determined by a pediatrician according to body weight and clinical condition.

Clinical Benefits:

• Provides strong anti-inflammatory action by inhibiting phospholipase a2 and reducing the production of prostaglandins, leukotrienes, and platelet-activating factor.
• Offers potent immunosuppressive effects through negative regulation of cytokine gene expression in macrophages, endothelial cells, and lymphocytes, thereby decreasing interleukin and other inflammatory mediators.
• Helps relieve symptoms such as swelling, redness, itching, and pain associated with inflammatory and allergic disorders.
• Improves breathing and reduces airway inflammation in steroid-responsive respiratory conditions when used as part of a comprehensive treatment plan.
• Liquid syrup form facilitates dosing in patients who have difficulty swallowing tablets, including children and elderly patients, allowing more precise dose adjustments.

Warnings & Contraindications:

• Use only under medical supervision. Long-term or high-dose use of systemic corticosteroids may cause serious side effects and requires regular medical follow-up.
• Contraindicated in patients with known hypersensitivity to prednisolone or any component of the formulation.
• Use with extreme caution in patients with active or latent infections (including tuberculosis, fungal, viral, or bacterial infections), as corticosteroids may mask signs of infection and worsen the condition.
• Use cautiously in patients with peptic ulcer disease, gastritis, esophagitis, osteoporosis, uncontrolled hypertension, heart failure, diabetes mellitus, glaucoma, cataracts, psychiatric disorders, or renal/hepatic impairment.
• Live or live-attenuated vaccines are generally not recommended during high-dose systemic corticosteroid therapy; consult your doctor before any vaccination.
• Prednisolone may affect growth in children with prolonged use; pediatric patients on long-term therapy should be monitored regularly.
• Consult your doctor before use if pregnant or planning pregnancy. Corticosteroids should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus.
• Breastfeeding women should consult their doctor before use, as prednisolone can be excreted in breast milk.
• Patients with diabetes should monitor blood glucose closely, as corticosteroids can increase blood sugar levels.
• Do not use this product without medical advice for minor conditions or self-diagnosed illnesses.
• Consult your doctor before use if you are taking other medications, including nonsteroidal anti-inflammatory drugs (nsaids), anticoagulants, antidiabetic agents, antihypertensives, anticonvulsants, or other immunosuppressants, due to potential drug interactions.
• Not intended to diagnose, treat, cure, or prevent any disease without appropriate medical evaluation and prescription.
• Keep out of reach of children.

Side Effects:

• Common side effects (especially with prolonged or high-dose use) may include increased appetite, weight gain, mood changes (irritability, euphoria, insomnia), indigestion, and fluid retention.
• Metabolic and endocrine effects may include elevated blood sugar levels, worsening of diabetes, Cushingoid features (moon face, central obesity), and suppression of adrenal gland function.
• Musculoskeletal effects may include muscle weakness, osteoporosis, and increased risk of fractures with long-term use.
• Gastrointestinal effects may include stomach irritation, nausea, vomiting, and increased risk of peptic ulcers, especially when combined with nsaids.
• Ophthalmic effects can include increased intraocular pressure, glaucoma, and cataract formation with prolonged therapy.
• Immune effects include increased susceptibility to infections and masking of infection signs and symptoms.
• Serious reactions such as severe allergic reactions, severe mood or behavioral changes, vision problems, or signs of infection (fever, persistent sore throat) require immediate medical attention.
• Not all possible side effects are listed. Consult your doctor or pharmacist if you notice any unusual symptoms or if side effects become severe or persistent.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date stated on the package. Refer to the product label for any specific temperature requirements if provided.

Specifications:

• Product form: Oral syrup.
• Strength: 15 mg prednisolone per 5 ml.
• Pack size: 100 ml bottle.
• Route of administration: Oral.
• Intended use: Prescription-only systemic corticosteroid medicine for inflammatory and allergic conditions, as directed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.