Xilone Syrup

Xilone Syrup

Description:

Xilone Syrup is a prescription oral corticosteroid medicine containing prednisolone, a systemic synthetic glucocorticoid with potent anti-inflammatory and immunosuppressive properties. It is commonly used in the management of a wide range of inflammatory, allergic, and autoimmune conditions, as well as certain respiratory and rheumatic diseases. Xilone Syrup is designed for accurate dosing in liquid form, making it suitable for patients who have difficulty swallowing tablets, including children and older adults, under strict medical supervision.

Indications:

• Management of acute and chronic inflammatory conditions responsive to corticosteroids (as prescribed by a physician).
• Treatment of severe allergic reactions and hypersensitivity conditions such as severe asthma exacerbations, allergic rhinitis, and allergic skin reactions (e.g., urticaria, eczema), when systemic steroids are indicated.
• Adjunctive therapy in bronchial asthma and other obstructive airway diseases requiring systemic corticosteroids.
• Autoimmune and rheumatic disorders (e.g., rheumatoid arthritis, systemic lupus erythematosus) as directed by a specialist.
• Endocrine disorders such as adrenal insufficiency where glucocorticoid replacement is indicated (according to physician’s judgment).
• Dermatologic, hematologic, and other systemic conditions where systemic glucocorticoids are recommended.
• Used only under medical supervision; specific indication, dose, and duration must be determined by the treating doctor.

Active Ingredients / Key Components:

• Prednisolone – concentration in mg per 5 ml is not specified in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.) (exact strength not available).
• Excipients (such as solvents, sweeteners, stabilizers, and preservatives) are present to form the syrup base; detailed composition is not available.

Dosage & Administration / How to Use:

• Use Xilone Syrup exactly as prescribed by your physician. Do not adjust the dose or stop treatment without medical advice.
• The dose is usually calculated based on the patient’s body weight, age, and the severity of the condition. Your doctor will determine the appropriate mg of prednisolone per day and corresponding volume of syrup.
• Typical administration is once daily in the morning or divided into 2–3 doses per day, as directed by the doctor.
• Can generally be taken with or after food to help reduce gastric irritation, unless your doctor advises otherwise.
• Shake the bottle well before each use to ensure uniform distribution of the active ingredient.
• Measure the dose carefully using a calibrated measuring spoon, oral syringe, or cup provided by the pharmacist. Do not use household teaspoons.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Do not stop Xilone Syrup abruptly after prolonged use; the dose must be tapered gradually under medical supervision to avoid adrenal insufficiency.
• Duration of treatment varies from short courses (for acute conditions) to longer regimens (for chronic diseases) and must be strictly individualized by the physician.

Clinical Benefits:

• Provides strong anti-inflammatory action by inhibiting phospholipase a2 and reducing the production of prostaglandins, leukotrienes, and platelet-activating factor.
• Offers effective immunosuppressive effects by downregulating cytokine gene expression in macrophages, endothelial cells, and lymphocytes, helping control autoimmune and hypersensitivity reactions.
• Helps relieve symptoms such as swelling, redness, pain, and itching associated with inflammatory and allergic conditions.
• Supports better control of acute asthma attacks and other severe respiratory exacerbations when systemic steroids are indicated.
• Liquid syrup form facilitates easier swallowing and more flexible dosing, especially in pediatric and elderly patients who may not tolerate tablets.

Warnings & Contraindications:

• Use only under medical supervision. Long-term or high-dose use can cause serious side effects and must be regularly monitored by a healthcare professional.
• Contraindicated in patients with known hypersensitivity to prednisolone or any component of the formulation.
• Systemic corticosteroids may increase susceptibility to infections and may mask signs of infection. Use with extreme caution in patients with active or latent infections (e.g., tuberculosis, fungal, viral, or bacterial infections).
• Use cautiously in patients with diabetes, hypertension, peptic ulcer disease, osteoporosis, glaucoma, cataracts, psychiatric disorders, heart failure, or kidney or liver impairment.
• May cause adrenal suppression; abrupt discontinuation after prolonged therapy can lead to acute adrenal insufficiency. Tapering is required under medical supervision.
• Live vaccines are generally contraindicated during systemic corticosteroid therapy at immunosuppressive doses. Consult your doctor before any vaccination.
• Pregnancy and breastfeeding: Use only if clearly needed and prescribed by a physician after assessing benefit–risk. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
• Children on prolonged therapy require careful growth and development monitoring due to the risk of growth suppression.
• May cause mood changes, behavioral disturbances, or psychiatric symptoms; patients and caregivers should report unusual mood or mental changes promptly.
• Consult your doctor before use if pregnant, nursing, taking other medications (especially other steroids, antidiabetics, anticoagulants, NSAIDs, or immunosuppressants), or have chronic medical conditions such as liver disease, kidney disease, diabetes, hypertension, or heart disease.
• Not intended to diagnose, treat, cure, or prevent any disease without a doctor’s prescription and supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects (especially with prolonged or high-dose use) may include increased appetite, weight gain, fluid retention, facial puffiness, mood changes, irritability, insomnia, and indigestion.
• Other possible effects: elevated blood pressure, increased blood sugar levels, muscle weakness, thinning of the skin, easy bruising, delayed wound healing, acne, and increased susceptibility to infections.
• Long-term use may lead to osteoporosis, cataracts, glaucoma, menstrual irregularities, growth suppression in children, and adrenal suppression.
• Serious reactions such as severe allergic reactions, severe abdominal pain, black or bloody stools, vision changes, severe mood or behavioral changes, or signs of infection (fever, sore throat, persistent cough) require immediate medical attention.
• Inform your doctor or pharmacist about any side effects you experience, especially if they are severe, persistent, or worsening.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date stated on the packaging. Follow any additional storage instructions provided on the label or by your pharmacist.

Specifications:

• Product form: oral syrup.
• Active ingredient: prednisolone (exact mg per 5 ml not available in the provided information).
• Intended use: prescription systemic corticosteroid for inflammatory, allergic, and autoimmune conditions, as directed by a physician.
• Suitable for: adults and children as prescribed; dose and duration must be individualized.
• Pack size and bottle volume: specific size in ml is not available in the provided information.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.