Zanoglide 4/30 Mg 30 Tablets

Zanoglide 4/30 Mg 30 Tablets

Description:

Zanoglide 4/30 mg 30 tablets is an oral antidiabetic prescription medicine used for the management of type 2 diabetes mellitus in adults. It combines two active ingredients, glimepiride and pioglitazone, to help control blood glucose levels when diet and exercise alone are not sufficient, or when other single oral antidiabetic agents are inadequate. Zanoglide belongs to the class of insulin secretagogues (sulfonylureas) and thiazolidinediones, offering a dual mechanism: increasing insulin release from the pancreas and improving insulin sensitivity in peripheral tissues. It is part of comprehensive diabetes care to reduce the risk of diabetes-related complications when used under medical supervision.

Indications:

• Type 2 diabetes mellitus in adults, particularly in patients who are insufficiently controlled on glimepiride or pioglitazone alone, or in combination with other oral antidiabetic medications as directed by a physician.
• Helps lower elevated fasting and postprandial (after-meal) blood glucose levels.
• Used as part of a comprehensive diabetes management plan that includes diet, exercise, and regular blood glucose monitoring.

Active Ingredients / Key Components:

• Glimepiride – 4 mg per tablet (third-generation sulfonylurea oral antidiabetic agent).
• Pioglitazone – 30 mg per tablet (thiazolidinedione class insulin sensitizer).
• Excipients: Information on inactive ingredients (excipients, fillers, coloring agents, preservatives) is not available in the provided data. Please refer to the official package insert for the full excipient list.

Dosage & Administration / How to Use:

• Dosage must always be individualized by the treating physician based on blood glucose response, previous therapy, and overall clinical condition.
• Typical adult dose: As prescribed by your doctor, commonly 1 tablet once daily; some patients may require dose adjustment (frequency and strength) according to medical advice.
• Administration: Swallow the tablet whole with a sufficient amount of water. Do not crush or chew unless your doctor or pharmacist advises otherwise.
• Timing: Usually taken once daily with breakfast or the first main meal of the day to reduce the risk of hypoglycemia. Follow your doctor’s specific instructions.
• Do not skip meals while on this medication, as this may increase the risk of low blood sugar (hypoglycemia).
• If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed one.
• Use in combination: May be used alone or in combination with other antidiabetic agents (such as metformin or insulin) only under strict medical supervision.

Clinical Benefits:

• Provides dual action blood glucose control by increasing insulin secretion (glimepiride) and enhancing insulin sensitivity in muscle, fat, and liver tissues (pioglitazone).
• Helps improve overall glycemic control, including fasting and postprandial blood glucose levels, which may contribute to reduced risk of long-term diabetes complications when used consistently with lifestyle measures.
• Glimepiride stimulates pancreatic beta cells via sulfonylurea receptors, enhancing second-phase insulin secretion and improving glucose tolerance.
• Pioglitazone improves peripheral insulin sensitivity and reduces insulin resistance, allowing better utilization of glucose by target tissues.
• May reduce hepatic glucose production and improve lipid profile parameters in some patients, as part of comprehensive metabolic management (as evaluated by the treating physician).

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to glimepiride, pioglitazone, other sulfonylureas, sulfonamides, or any component of the formulation.
• Not indicated for type 1 diabetes mellitus or for the treatment of diabetic ketoacidosis.
• Use with caution in patients with hepatic impairment, renal impairment, heart failure, or a history of cardiovascular disease. Pioglitazone may cause or exacerbate congestive heart failure.
• May cause hypoglycemia, especially in elderly patients, those with irregular meals, intense physical exercise, or in combination with other glucose-lowering agents or alcohol.
• Pioglitazone has been associated with fluid retention, edema, and possible increased risk of bone fractures in some patients.
• Regular monitoring of liver function tests, blood glucose, and HbA1c is recommended during treatment.
• Consult your doctor before use if pregnant, planning pregnancy, or breastfeeding. Many oral antidiabetics are not recommended during pregnancy; insulin may be preferred.
• Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, as drug interactions may alter blood glucose levels.
• Not intended to diagnose, treat, cure, or prevent any disease without appropriate medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects: Hypoglycemia (low blood sugar) presenting with symptoms such as sweating, tremor, hunger, palpitations, dizziness, headache, or confusion; weight gain; mild edema; and gastrointestinal disturbances such as nausea or stomach discomfort.
• Less common side effects: Visual disturbances, fatigue, upper respiratory tract infections, and mild anemia or changes in blood counts.
• Serious side effects (seek immediate medical attention): Severe hypoglycemia, signs of heart failure (shortness of breath, rapid weight gain, swelling of legs or ankles), chest pain, jaundice or dark urine (possible liver dysfunction), severe allergic reactions (rash, itching, swelling, difficulty breathing), or unusual bone pain or fractures.
• If you experience persistent or severe side effects, contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight and moisture. Keep the blister pack or container tightly closed. Do not use after the expiry date printed on the pack. Keep out of reach of children.

Specifications:

• Form: Oral tablets.
• Strength: Each tablet contains glimepiride 4 mg and pioglitazone 30 mg.
• Pack size: 30 tablets per pack.
• Intended use: Prescription antidiabetic medicine for adults with type 2 diabetes mellitus.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.