Zestril 20 Mg 10 Tablets

Zestril 20 Mg 10 Tablets

Description:

Zestril 20 mg 10 tablets is a prescription antihypertensive medicine containing lisinopril, an angiotensin-converting enzyme (ace) inhibitor. It is used to lower high blood pressure and to protect the heart and kidneys in certain cardiovascular and renal conditions. By blocking the conversion of angiotensin i to angiotensin ii, Zestril helps relax and widen blood vessels, reduce sodium and water retention, and decrease total peripheral resistance, leading to a controlled reduction in blood pressure while maintaining adequate blood flow to vital organs.

Indications:

• Treatment of essential (primary) hypertension in adults.
• Treatment of renovascular hypertension and other forms of secondary hypertension, as prescribed by a physician.
• Management of heart failure (as part of combination therapy) to reduce symptoms and improve survival, as directed by a cardiologist.
• Post-myocardial infarction: to improve survival and reduce the risk of further cardiovascular events in clinically stable patients (when indicated by a specialist).
• Diabetic nephropathy and other proteinuric kidney diseases (especially in patients with hypertension) to help protect kidney function, as advised by a nephrologist.
• Helps reduce the risk of complications associated with uncontrolled high blood pressure such as stroke, heart attack, and kidney damage.

Active Ingredients / Key Components:

• Lisinopril (as lisinopril dihydrate) – 20 mg per tablet.
• Excipients: tablet core and coating excipients (such as fillers, binders, and stabilizers). Exact excipient list and concentrations , please check the product leaflet or the manufacturer’s official website; please refer to the official package leaflet for full details.

Dosage & Administration / How to Use:

• Use Zestril 20 mg only as prescribed by your doctor. Do not change your dose or stop treatment without medical advice.
• Typical adult dose for hypertension: the usual maintenance dose ranges from 10 mg to 40 mg once daily. Zestril 20 mg is commonly used as a once-daily dose or in combination with other strengths, according to blood pressure response. The exact dose must be individualized by the physician.
• Heart failure: usually started at a lower dose (e.g., 2.5–5 mg once daily) and gradually increased under close medical supervision. Zestril 20 mg may be used as a maintenance dose if tolerated and indicated.
• Post-myocardial infarction and kidney protection: dosing and titration schedule are determined by the treating specialist based on clinical status and kidney function.
• Administration: swallow the tablet whole with a glass of water. It can be taken with or without food, but try to take it at the same time each day for best blood pressure control.
• If you miss a dose: take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed tablet.
• Regular monitoring: blood pressure, kidney function (serum creatinine, egfr), and serum potassium should be checked regularly during treatment, especially after dose changes or in patients with kidney disease, heart failure, or those taking diuretics.

Clinical Benefits:

• Effectively lowers both systolic and diastolic blood pressure by dilating arterioles and reducing total peripheral resistance.
• Helps reduce sodium and water retention by decreasing aldosterone secretion, supporting better blood pressure and fluid balance control.
• Maintains cardiac output and cardiovascular reflexes, with minimal effect on capacitance vessels, so postural (orthostatic) hypotension is less likely compared with some other antihypertensives.
• Preserves renal, cerebral, and coronary blood flow while lowering blood pressure, supporting protection of vital organs.
• Reduces the risk of long-term complications of uncontrolled hypertension such as stroke, heart attack, heart failure, and progressive kidney damage.
• Can provide greater blood pressure reduction in patients with high renin-angiotensin activity, such as those with renovascular, accelerated, or malignant hypertension, under specialist supervision.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to lisinopril, any ace inhibitor, or any component of the formulation.
• Do not use if you have a history of angioedema (hereditary, idiopathic, or previous angioedema associated with ace inhibitor therapy).
• Contraindicated during pregnancy, especially in the second and third trimesters, due to risk of serious fetal harm (including fetal kidney damage, oligohydramnios, and death). If pregnancy is detected, discontinue Zestril as soon as possible.
• Not recommended during breastfeeding unless specifically advised by a doctor, as lisinopril may pass into breast milk.
• Use with caution in patients with kidney impairment, renal artery stenosis, dehydration, heart failure, or those on diuretics, potassium-sparing diuretics, potassium supplements, or other drugs that increase serum potassium.
• May cause symptomatic hypotension, especially after the first dose or dose increase, in volume-depleted patients (e.g., due to diuretics, vomiting, diarrhea, or salt restriction). Medical supervision is advised when initiating therapy.
• Monitor renal function and serum potassium regularly, particularly in patients with kidney disease, diabetes, or those taking nephrotoxic or potassium-elevating drugs.
• Use with caution in patients with aortic stenosis, hypertrophic cardiomyopathy, or other conditions where excessive blood pressure reduction may compromise organ perfusion.
• Inform your doctor about all medicines you are taking, especially diuretics, other antihypertensives, non-steroidal anti-inflammatory drugs (nsaids), lithium, potassium supplements, or potassium-sparing diuretics.
• Consult your doctor before use if pregnant, nursing, taking medications, or have medical conditions such as kidney disease, liver disease, heart failure, diabetes, or vascular disease.
• Keep out of reach of children.

Side Effects:

• Common side effects may include dizziness, headache, fatigue, low blood pressure (especially after the first doses), dry persistent cough, nausea, or diarrhea.
• Less common side effects can include rash, itching, changes in taste, elevated blood potassium (hyperkalemia), or mild kidney function changes.
• Serious side effects (seek immediate medical attention): swelling of the face, lips, tongue, or throat (angioedema), difficulty breathing or swallowing, severe dizziness or fainting, severe abdominal pain, or marked decrease in urine output.
• If you experience any unusual or persistent symptoms, contact your doctor or pharmacist promptly.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Do not use after the expiry date stated on the package. Store at or below the temperature recommended on the official packaging (exact temperature range is not available in the provided information; refer to the product carton or leaflet).

Specifications:

• Product type: prescription antihypertensive medicine (ace inhibitor).
• Active ingredient: lisinopril 20 mg per tablet.
• Form: oral tablet.
• Pack size: 10 tablets per pack.
• Intended users: adults, as prescribed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.