Erastapex Trio /5/12.5 40 Mg 30 Tablets

Erastapex Trio /5/12.5 40 Mg 30 Tablets

Description:

Erastapex Trio 5/20/12.5 mg film‑coated tablets is a prescription antihypertensive medicine that combines three active ingredients: amlodipine, olmesartan, and hydrochlorothiazide. It is used for the long‑term management of high blood pressure (hypertension) in adults who require combination therapy to achieve adequate blood pressure control. By combining a calcium channel blocker, an angiotensin II receptor blocker (ARB), and a thiazide diuretic in one tablet, Erastapex Trio helps reduce blood pressure effectively, supports cardiovascular health, and improves treatment adherence by simplifying dosing.

Indications:

• Treatment of essential hypertension (high blood pressure) in adults.
• Patients whose blood pressure is not adequately controlled with dual therapy (e.g., amlodipine/olmesartan or olmesartan/hydrochlorothiazide) and who require triple combination therapy.
• Helps reduce the risk of hypertension‑related complications such as stroke, heart attack, and kidney damage when used as part of an overall cardiovascular risk‑reduction plan as directed by a physician.

Active Ingredients / Key Components:

• Amlodipine – 5 mg (calcium channel blocker; dihydropyridine type)
• Olmesartan medoxomil – 20 mg (angiotensin II receptor blocker – ARB)
• Hydrochlorothiazide – 12.5 mg (thiazide diuretic)
• Other excipients: film‑coating agents and tablet core excipients (full excipient list is not available in the provided data; please refer to the official package leaflet for complete information).

Dosage & Administration / How to Use:

• Erastapex Trio is for oral use only and should be taken exactly as prescribed by your physician.
• Usual adult dose: one tablet once daily, preferably at the same time each day. The exact dose and strength are determined by the doctor based on blood pressure response and prior therapy.
• Can be taken with or without food; swallow the tablet whole with a glass of water. Do not crush, chew, or split the film‑coated tablet.
• If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed tablet.
• Do not stop taking Erastapex Trio suddenly without medical advice, as this may cause your blood pressure to rise again.
• Regular monitoring of blood pressure, kidney function, and electrolytes (especially potassium and sodium) is recommended during treatment.

Clinical Benefits:

• Provides triple‑mechanism blood pressure control by combining a calcium channel blocker, an ARB, and a thiazide diuretic in a single tablet.
• Amlodipine promotes peripheral arterial vasodilation, reducing peripheral vascular resistance and lowering blood pressure.
• Olmesartan blocks the vasoconstrictor and aldosterone‑secreting effects of angiotensin II, leading to relaxation of blood vessels and improved blood pressure control.
• Hydrochlorothiazide increases the excretion of sodium and water, reducing blood volume and helping to lower blood pressure.
• Improves treatment adherence and convenience by reducing the number of separate antihypertensive tablets needed each day.
• Supports long‑term cardiovascular protection when used as part of a comprehensive management plan including diet, exercise, and lifestyle modification.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to amlodipine, olmesartan, hydrochlorothiazide, other dihydropyridines, sulfonamide‑derived drugs, or any component of the formulation.
• Contraindicated in pregnancy: ARBs can cause injury and death to the developing fetus. If pregnancy is detected, stop Erastapex Trio as soon as possible and contact your doctor immediately.
• Not recommended during breastfeeding unless clearly needed and prescribed by a physician.
• Contraindicated in severe kidney impairment, anuria (inability to produce urine), severe liver impairment, or refractory hypokalemia/hypercalcemia related to thiazide use.
• Use with caution in patients with renal artery stenosis, heart failure, severe aortic stenosis, hypertrophic cardiomyopathy, electrolyte imbalances, gout, diabetes, or a history of angioedema.
• May cause symptomatic hypotension, especially in volume‑depleted patients (e.g., those on high‑dose diuretics, low‑salt diet, vomiting, or diarrhea). Start under medical supervision.
• Hydrochlorothiazide may increase uric acid and blood glucose levels; caution in patients with gout or diabetes.
• Photosensitivity reactions have been reported with thiazide diuretics; avoid excessive sun exposure and use adequate sun protection.
• Drug interactions: use caution with other antihypertensives, potassium‑sparing diuretics, potassium supplements, lithium, NSAIDs, and certain antidiabetic drugs. Inform your doctor about all medicines and supplements you are taking.
• Consult your doctor before use if pregnant, nursing, taking other medications, or if you have medical conditions such as kidney disease, liver disease, heart disease, diabetes, or electrolyte disturbances.
• Keep out of reach of children.

Side Effects:

• Common side effects may include dizziness, headache, flushing, ankle or leg swelling (peripheral edema), fatigue, nausea, abdominal discomfort, or palpitations.
• Hydrochlorothiazide‑related effects can include increased urination, low blood pressure, muscle cramps, electrolyte disturbances (low potassium, low sodium), increased uric acid, or mild increases in blood glucose or cholesterol.
• Less common but serious side effects may include severe hypotension, allergic reactions, angioedema (swelling of face, lips, tongue, or throat), severe skin reactions, jaundice or liver dysfunction, kidney function deterioration, or severe electrolyte imbalance.
• Seek immediate medical attention if you experience difficulty breathing, chest pain, severe dizziness or fainting, marked swelling of the face or throat, or signs of severe skin reaction.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.

Specifications:

• Product type: Prescription antihypertensive medicine (triple combination).
• Form: Film‑coated tablet.
• Strength per tablet: amlodipine 5 mg + olmesartan medoxomil 20 mg + hydrochlorothiazide 12.5 mg.
• Pack size: 30 tablets (30 f.c. tabs) – typically a 1‑month supply for once‑daily dosing, depending on physician instructions.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.