Augmentin Duo \ 200\28 Mg 5 ml

Augmentin Duo \ 200\28 Mg 5 ml

Description:

Augmentin Duo 228 mg/5 ml suspension is a prescription systemic antibiotic medicine from GlaxoSmithKline that combines amoxicillin and clavulanic acid to treat a wide range of bacterial infections in adults and children. It belongs to the penicillin/beta-lactamase inhibitor class and is formulated as an oral suspension for easier dosing, especially in pediatric patients. By inhibiting bacterial cell wall synthesis and blocking beta-lactamase enzymes, Augmentin Duo is effective against many beta-lactamase–producing bacteria that are resistant to amoxicillin alone.

Indications:

• Lower respiratory tract infections, including bronchitis and pneumonia, caused by beta-lactamase–producing isolates of Haemophilus influenzae and Moraxella catarrhalis.
• Acute bacterial otitis media (middle ear infection) caused by beta-lactamase–producing isolates of H. influenzae and M. catarrhalis.
• Acute bacterial sinusitis caused by beta-lactamase–producing isolates of H. influenzae and M. catarrhalis.
• Skin and skin structure infections caused by beta-lactamase–producing isolates of Staphylococcus aureus, Escherichia coli, and Klebsiella species.
• Urinary tract infections (UTIs) caused by beta-lactamase–producing isolates of E. coli, Klebsiella species, and Enterobacter species.
• Other susceptible infections as determined by culture, sensitivity testing, and physician judgment.

Active Ingredients / Key Components:

• Amoxicillin (as amoxicillin trihydrate) – 200 mg per 5 ml oral suspension.
• Clavulanic acid (as potassium clavulanate) – 28 mg per 5 ml oral suspension.
• Concentration ratio: 200 mg amoxicillin : 28 mg clavulanic acid per 5 ml (total 228 mg/5 ml).
• Excipients: Full list of inactive ingredients (such as suspending agents, sweeteners, flavoring agents, and preservatives) is not provided in the available data. Please refer to the official package insert for the complete excipient list.

Dosage & Administration / How to Use:

• Augmentin Duo 228 mg/5 ml is for oral use only and should be taken exactly as prescribed by a physician.
• Shake the bottle well before each use to ensure uniform suspension.
• Use a calibrated oral syringe or measuring spoon to ensure accurate dosing; do not use household teaspoons.
• Recommended pediatric and adult doses depend on body weight, age, infection severity, and kidney function. Typical pediatric dosing is based on the amoxicillin component (mg/kg/day) divided into 2 or 3 doses per day, as directed by the doctor. Exact dosing regimen must be determined by the prescribing physician.
• It is generally recommended to take Augmentin with food to improve absorption and reduce gastrointestinal side effects.
• Duration of treatment usually ranges from 5 to 14 days depending on the type and severity of infection; complete the full course even if symptoms improve earlier.
• If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.
• Do not stop treatment without consulting your doctor, as this may lead to relapse or antibiotic resistance.

Clinical Benefits:

• Broad-spectrum antibacterial action against many beta-lactamase–producing organisms that are resistant to amoxicillin alone.
• Effective treatment of respiratory infections such as sinusitis, otitis media, bronchitis, and pneumonia, helping relieve symptoms like fever, cough, ear pain, and nasal congestion caused by susceptible bacteria.
• Helps resolve skin and soft tissue infections, reducing redness, swelling, pain, and pus formation when due to susceptible organisms.
• Provides reliable therapy for urinary tract infections caused by beta-lactamase–producing bacteria, helping relieve dysuria, frequency, and urinary discomfort.

Warnings & Contraindications:

• Contraindicated in patients with a known hypersensitivity to amoxicillin, clavulanic acid, other penicillins, or any component of the formulation.
• Use with extreme caution in patients with a history of severe allergic reactions to beta-lactam antibiotics (penicillins, cephalosporins, carbapenems); serious reactions, including anaphylaxis, can occur.
• Patients with hepatic impairment or a history of cholestatic jaundice or liver dysfunction associated with amoxicillin/clavulanate should not use this product unless clearly needed and under strict medical supervision.
• Use with caution in patients with renal impairment; dose adjustment may be required based on kidney function.
• Prolonged use may result in overgrowth of non-susceptible organisms, including fungi; if superinfection occurs, appropriate measures should be taken.
• Antibiotic-associated colitis, including Clostridioides difficile–associated diarrhea, may occur; if severe or persistent diarrhea develops, contact a healthcare professional immediately.
• Consult your doctor before use if pregnant or breastfeeding. Amoxicillin and clavulanic acid cross the placenta and are excreted in breast milk; benefits and risks must be assessed by the physician.
• Inform your doctor about all medications you are taking, especially anticoagulants (e.g., warfarin), allopurinol, methotrexate, or other antibiotics, due to potential interactions.
• Not intended for viral infections such as the common cold or influenza; misuse can contribute to antibiotic resistance.
• Keep out of reach of children.

Side Effects:

• Common side effects: nausea, vomiting, diarrhea, abdominal pain, indigestion, and mild skin rash.
• Less common side effects: headache, dizziness, oral or vaginal candidiasis (thrush), and changes in taste.
• Serious side effects (seek immediate medical attention): severe allergic reactions (rash, itching, swelling of face/lips/tongue/throat, difficulty breathing), severe or persistent diarrhea, blood in stools, yellowing of the skin or eyes (jaundice), dark urine, unusual bruising or bleeding, or severe skin reactions.
• If any side effects persist, worsen, or if you notice any other unusual symptoms, contact your doctor or pharmacist promptly.

Storage Instructions:

Store the dry powder bottle below 25°c, protected from moisture and direct sunlight, with the cap tightly closed. After reconstitution with water, store the prepared suspension in a refrigerator (usually 2–8°c) and use within the period specified in the package insert (commonly up to 7 days); discard any unused portion after this period. Do not freeze. Keep out of reach of children.

Specifications:

• Product type: Prescription systemic antibiotic medicine.
• Form: Oral suspension (powder for reconstitution).
• Strength: 228 mg/5 ml (200 mg amoxicillin + 28 mg clavulanic acid per 5 ml).
• Pack size: 70 ml suspension after reconstitution (as indicated: 228 mg/5 ml susp. 70 ml).
• Route of administration: Oral.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.