Cholerose Plus 40/10 28Tab

Cholerose Plus 40/10 28Tab

Description:

Cholerose Plus 40/10 28Tab is a prescription lipid-lowering medicine that combines two active ingredients, rosuvastatin and ezetimibe, in one film-coated tablet. It is used as part of a comprehensive cholesterol management plan, including diet and lifestyle changes, to help reduce elevated total cholesterol, LDL ("bad") cholesterol, and non-HDL cholesterol, and to support cardiovascular risk reduction in appropriate patients. This product is intended for adult use under medical supervision.

Indications:

• Treatment of primary hypercholesterolemia (high cholesterol), including familial and non-familial forms, when a combination of rosuvastatin and ezetimibe is appropriate.
• Reduction of elevated LDL-cholesterol, total cholesterol, non-HDL cholesterol and apoB in patients not adequately controlled on statin or ezetimibe monotherapy.
• Adjunct to diet and lifestyle modification (low-fat diet, weight control, physical activity) for patients at high or very high risk of cardiovascular events who require intensive lipid-lowering therapy.
• May be used in patients who are already stabilized on separate tablets of rosuvastatin and ezetimibe at equivalent doses, to simplify therapy to a single tablet, as directed by the physician.

Active Ingredients / Key Components:

• Rosuvastatin – 40 mg per film-coated tablet (exact strength inferred from product name 40/10; confirm on package or leaflet as local product information may vary).
• Ezetimibe – 10 mg per film-coated tablet (exact strength inferred from product name 40/10; confirm on package or leaflet as local product information may vary).
• Other tablet excipients: Full list of inactive ingredients (excipients, colorants, coating agents, preservatives) is not available in the provided data. Please refer to the official package leaflet for the complete composition.

Dosage & Administration / How to Use:

• Use only as prescribed by your physician. Do not change your dose without medical advice.
• Typical adult dose: 1 tablet once daily, preferably at the same time each day. The exact dose and duration are determined by your doctor based on your cholesterol levels, cardiovascular risk, and response to treatment.
• Can be taken with or without food. Swallow the tablet whole with a glass of water; do not crush or chew.
• Continue following a cholesterol-lowering diet and lifestyle program (healthy diet, exercise, weight control, smoking cessation) during treatment.
• If you miss a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose. Do not take a double dose to make up for a forgotten tablet.
• Regular monitoring: Your doctor may request blood tests to check liver function, kidney function, and lipid profile before and during treatment, and may adjust the dose accordingly.
• Do not stop taking Cholerose Plus 40/10 without consulting your doctor, as cholesterol levels may rise again.

Clinical Benefits:

• Provides dual cholesterol control by inhibiting cholesterol synthesis in the liver (rosuvastatin) and reducing cholesterol absorption from the intestine (ezetimibe).
• Helps significantly lower LDL ("bad") cholesterol, total cholesterol, and non-HDL cholesterol in patients requiring intensive lipid-lowering therapy.
• Supports reduction of triglycerides and may help increase HDL ("good") cholesterol in many patients as part of overall lipid profile improvement.
• Contributes to lowering cardiovascular risk (such as heart attack and stroke) in high-risk patients when used along with diet, lifestyle changes, and other prescribed therapies.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to rosuvastatin, ezetimibe, or any of the excipients.
• Contraindicated in patients with active liver disease or unexplained persistent elevations of serum transaminases.
• Contraindicated during pregnancy and breastfeeding. Women of childbearing potential should use effective contraception during treatment.
• Use with caution in patients with kidney impairment, history of liver disease, hypothyroidism, or excessive alcohol consumption.
• Risk of muscle-related side effects (myopathy, rhabdomyolysis) may increase when used with certain medicines (e.g., some fibrates, niacin in high doses, ciclosporin, certain antivirals). Inform your doctor about all medications and supplements you are taking.
• Report immediately any unexplained muscle pain, tenderness, weakness, or cramps, especially if accompanied by fever or malaise.
• May slightly increase blood sugar levels; use with caution in patients with diabetes or at risk of diabetes.
• Consult your doctor before use if pregnant, nursing, planning pregnancy, taking other lipid-lowering drugs, anticoagulants, immunosuppressants, or have medical conditions such as liver disease, kidney disease, thyroid disorders, or muscle disorders.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision.
• Keep out of reach of children.

Side Effects:

• Common side effects may include headache, dizziness, abdominal pain, nausea, constipation, diarrhea, flatulence, muscle pain, joint pain, or fatigue.
• Less common but potentially serious side effects include muscle weakness or pain, rhabdomyolysis (severe muscle breakdown), liver enzyme elevations, hepatitis, pancreatitis, or severe allergic reactions (rash, itching, swelling, difficulty breathing).
• Stop taking the medicine and seek immediate medical attention if you experience severe muscle pain, dark-colored urine, yellowing of the skin or eyes (jaundice), severe abdominal pain, or signs of allergic reaction.
• Not all possible side effects are listed. Refer to the official patient leaflet and consult your healthcare provider if you notice any unusual symptoms.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children.

Specifications:

• Product type: Prescription lipid-lowering medicine (rosuvastatin + ezetimibe combination).
• Strength: 40 mg rosuvastatin / 10 mg ezetimibe per film-coated tablet (strength inferred from product name; verify on pack).
• Form: Film-coated tablet.
• Pack size: 28 tablets per pack.
• Intended use: Adults, as prescribed by a physician, as part of a comprehensive cholesterol and cardiovascular risk management plan.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.