Xithrone 200 Mg/5 Susp 15 ml

Xithrone 200 Mg/5 Susp 15 ml

Description:

Xithrone 200 mg/5 ml suspension is an oral prescription antibiotic medicine containing azithromycin, a semi-synthetic macrolide of the azalide class. It is formulated as a ready-to-use oral suspension for the treatment of various bacterial infections, particularly of the respiratory tract, skin and soft tissues, and certain sexually transmitted and gastrointestinal infections. Xithrone works by inhibiting bacterial protein synthesis, thereby stopping the growth and multiplication of susceptible bacteria. This product is intended for use under medical supervision and is suitable for adults and children as directed by a physician.

Indications:

• Treatment of upper and lower respiratory tract infections caused by susceptible organisms (such as bronchitis, community-acquired pneumonia, pharyngitis, tonsillitis, and sinusitis).
• Skin and soft tissue infections (such as uncomplicated skin infections and soft tissue infections caused by susceptible bacteria).
• Some gastrointestinal infections, including typhoid fever, as prescribed by a doctor.
• Certain sexually transmitted infections (such as uncomplicated gonorrhoea, chlamydial urethritis, chancroid, and granuloma inguinale) when azithromycin is indicated and prescribed.
• Prophylaxis and treatment (in combination with other agents) of disseminated Mycobacterium avium complex (MAC) infections in at-risk patients, as directed by a specialist.
• Other infections caused by azithromycin-susceptible organisms, according to physician judgment and local guidelines.

Active Ingredients / Key Components:

• Azithromycin – 200 mg per 5 ml oral suspension (concentration based on product name and standard formulation).
• Inactive ingredients (excipients, sweeteners, stabilizers, flavoring agents, preservatives) – specific excipient list and concentrations are not provided in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.).

Dosage & Administration / How to Use:

• Use Xithrone 200 mg/5 ml suspension exactly as prescribed by your physician. Do not change the dose or duration without medical advice.
• Shake the bottle well before each use to ensure uniform suspension.
• Measure the dose accurately using the provided measuring spoon or oral syringe; do not use household teaspoons.
• Adults (typical azithromycin oral dosing – for reference only; your doctor may adjust):
  • Respiratory tract, skin and soft tissue infections: 500 mg once daily for 3 days, or 500 mg on day 1 followed by 250 mg once daily on days 2 to 5.
  • Typhoid fever: 500 mg once daily for 7 days.
  • Uncomplicated gonorrhoea: 2 g as a single dose.
  • Granuloma inguinale: 1 g initial dose, then 500 mg once daily until all lesions have completely healed.
  • Chancroid/Chlamydial urethritis: 1 g as a single dose.
  • Prophylaxis of disseminated MAC infections: 1.2 g once weekly. Treatment or secondary prophylaxis (with other antimycobacterials): 500 mg once daily.
• Pediatric dosing: The dose is usually based on body weight (mg/kg) and the type of infection. The pediatric regimen must be determined by the pediatrician; do not calculate or adjust doses on your own.
• Administration with food: Azithromycin suspension may be taken with or without food; if stomach upset occurs, taking it with food may help.
• Duration of therapy: Complete the full prescribed course even if symptoms improve early, to prevent relapse and antibiotic resistance.
• If a dose is missed: Take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to make up for a missed one.

Clinical Benefits:

• Broad-spectrum antibacterial activity against many common respiratory, skin, and soft tissue pathogens.
• Convenient once-daily dosing regimen, which may improve adherence compared with some other antibiotics.
• Short treatment courses (often 3–5 days) for many infections, while maintaining prolonged tissue levels due to a long half-life (~68 hours).
• Oral suspension form facilitates use in patients who have difficulty swallowing tablets, including children and some elderly patients.
• Effective tissue penetration, particularly in respiratory tissues, supporting its use in bronchitis and pneumonia when indicated.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to azithromycin, other macrolide or ketolide antibiotics, or any component of the formulation.
• Use with caution in patients with pre-existing liver disease or impaired liver function, as azithromycin is primarily eliminated by the liver.
• Use with caution in patients with renal impairment, significant cardiac disease, history of arrhythmias, or known QT interval prolongation, or those taking other drugs that prolong QT interval (risk of torsades de pointes).
• May cause Clostridioides difficile-associated diarrhea; persistent or severe diarrhea should be evaluated promptly by a physician.
• Antibiotic use may promote overgrowth of non-susceptible organisms, including fungi; if superinfection occurs, appropriate therapy should be instituted.
• Consult your doctor before use if pregnant or nursing; azithromycin should be used in pregnancy and lactation only if clearly needed and prescribed.
• Inform your doctor about all medications you are taking, especially antiarrhythmics, other macrolides, fluoroquinolones, antacids containing aluminum or magnesium, warfarin, digoxin, and other drugs metabolized by the liver.
• Not intended for viral infections such as common cold or influenza.
• Do not share this antibiotic with others, even if they have similar symptoms.
• Keep out of reach of children.

Side Effects:

• Common side effects may include nausea, vomiting, abdominal pain, diarrhea, flatulence, and mild digestive discomfort.
• Other possible effects: headache, dizziness, fatigue, taste disturbances, or mild skin rash.
• Serious side effects (seek immediate medical attention): severe or persistent diarrhea, blood or mucus in stool, severe abdominal cramps, signs of liver problems (yellowing of skin or eyes, dark urine, severe fatigue), severe allergic reactions (rash, itching, swelling of face/lips/tongue/throat, difficulty breathing), chest pain, palpitations, or fainting.
• If any unexpected or bothersome side effects occur, stop the medicine and contact your doctor or pharmacist.

Storage Instructions:

Store in a cool, dry place away from direct sunlight. Keep container tightly closed. Keep out of reach of children. Specific storage temperature and shelf-life after reconstitution (if applicable) are not provided in the available information (For full ingredient information, please check the product leaflet or the manufacturer’s official website.); follow the instructions on the package insert or as advised by your pharmacist.

Specifications:

• Product type: Oral antibiotic medicine (azithromycin suspension).
• Strength: 200 mg azithromycin per 5 ml suspension.
• Volume: 15 ml bottle.
• Form: Oral suspension.
• Intended users: Adults and children as directed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.